Evidence map›Paper›PMID 37050372›Full record

ArticlePolymers2023

Caffeine Release from Magneto-Responsive Hydrogels Controlled by External Magnetic Field and Calcium Ions and Its Effect on the Viability of Neuronal Cells.

Emilli C G Frachini, Jéssica S G Selva, Paula C Falcoswki, Jean B Silva, Daniel R Cornejo, Mauro Bertotti, Henning Ulrich, Denise F S Petri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Emilli C G FrachiniDepartament of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0002-6147-183X
Jéssica S G SelvaDepartament of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.
Paula C FalcoswkiDepartament of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.
Jean B SilvaDepartament of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.
Daniel R CornejoInstitute of Physics, University of São Paulo, São Paulo 05508-090, Brazil.
Mauro BertottiDepartament of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0001-9566-7577
Henning UlrichDepartament of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0002-2114-3815
Denise F S PetriDepartament of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0003-4814-8357
Universidade de São Paulo · BR

Funding

National Council for Scientific and Technological Development 304017/2021-3 and 141866/2016-0São Paulo Research Foundation 2018/13492-2, 2018/08782-1 and 2018/07366-4
6 · The paper itself

Abstract

Caffeine (CAF) is a psychostimulant present in many beverages and with rapid bioabsorption. For this reason, matrices that effectuate the sustained release of a low amount of CAF would help reduce the intake frequency and side effects caused by high doses of this stimulant. Thus, in this study, CAF was loaded into magnetic gelatin/alginate (Gel/Alg/MNP) hydrogels at 18.5 mg/g

Indexed as

alginateCa2+caffeinedrug deliverygelatinmagnetic hydrogelSH-SY5Y cells

Identifiers

PMID37050372
PMCPMC10097041
OpenAlexW4362587842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.