Evidence map›Paper›PMID 37050249›Full record

ArticlePolymers2023

Strategy Based on Michael Addition Reaction for the Development of Bioinspired Multilayered and Multiphasic 3D Constructs.

Mihaela Olaru, Natalia Simionescu, Florica Doroftei, Geta David

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mihaela Olaru"Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A Gr. Ghica Voda Alley, 700487 Iasi, Romania.
Natalia Simionescu"Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A Gr. Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0001-5581-4624
Florica Doroftei"Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A Gr. Ghica Voda Alley, 700487 Iasi, Romania.
Geta DavidDepartment of Natural and Synthetic Polymers, Faculty of Chemical Engineering and Environmental Protection "Cristofor Simionescu", "Gh. Asachi" Technical University of Iasi, 71A Bd. D. Mangeron, 700050 Iasi, Romania.
Romanian Academy · ROGheorghe Asachi Technical University of Iași · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high incidence of osteochondral defects has increased the interest in the development of improved repairing alternatives, with tissue engineering being considered a promising approach. The hierarchical, complex structure of osteochondral tissue requires the design of a biomimetic multilayered scaffold. Here, a multilayered and multiphasic 3D macroporous structure was achieved at subzero temperature by the Michael addition reaction of amino functionalities of collagen with acryloyl groups of a bifunctionalized poly(ε-caprolactone). This green approach has been successfully applied to crosslink layers of different composition, both for their efficient sequential formation and connection. Polyethylenimine functionalized nano-hydroxyapatite (nHAp

Indexed as

aza-Michael additionbiocompositecryogelationmultilayered constructtissue engineering

Identifiers

PMID37050249
PMCPMC10096539
OpenAlexW4361010966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.