Evidence map›Paper›PMID 37050230›Full record

ArticlePolymers2023

The Anti-Inflammatory Effect of Lactose-Modified Hyaluronic Acid Molecules on Primary Bronchial Fibroblasts of Smokers.

Alice Donato, Federico Fontana, Rina Venerando, Antonino Di Stefano, Paola Brun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alice DonatoHistology Unit, Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.
Federico FontanaCenter for Nanomedicine and Tissue Engineering, A.S.S.T. Grande Ospedale Metropolitano Niguarda, Piazza dell'Ospedale Maggiore 3, 20162 Milan, Italy.ORCID 0000-0001-9273-2556
Rina VenerandoDepartment of Molecular Medicine, University of Padova, 35121 Padova, Italy.
Antonino Di StefanoDivisione di Pneumologia e Laboratorio di Citoimmunopatologia dell'Apparato Cardio Respiratorio, Istituti Clinici Scientifici Maugeri, IRCCS, 28013 Gattico-Veruno, Italy.ORCID 0000-0003-3479-0875
Paola BrunHistology Unit, Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-4204-3549
University of Padua · ITIstituti Clinici Scientifici Maugeri · ITOspedale Maggiore · IT

Funding

Jointherapeutics s.r.l (Padua, Italy), University of Padova, Italy UNI - IMPRESA 2018
6 · The paper itself

Abstract

The progression of smoking-related diseases is characterized by macrophage-mediated inflammation, which is responsible for an increased expression of proinflammatory cytokines and galectins, molecules that bind specifically to β-galactoside sugars. This study aimed to assess the anti-inflammatory and antioxidant effects of a broad selection of differently lactose-modified hyaluronic acids (HA) named HYLACH

Indexed as

COPDGalectin 3hyaluronic acidinflammationreactive oxygen speciesrehabilitationsmoking

Identifiers

PMID37050230
PMCPMC10096707
OpenAlexW4360860505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.