Evidence map›Paper›PMID 37050007›Full record

ArticleMolecules (Basel, Switzerland)2023

Hydrogel-Film-Fabricated Fluorescent Biosensors with Aggregation-Induced Emission for Albumin Detection through the Real-Time Modulation of a Vortex Fluidic Device.

Qi Hu, Xuan Luo, Damian Tohl, Anh Tran Tam Pham, Colin Raston, Youhong Tang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qi HuAustralia-China Joint Research Centre on Personal Health Technologies, Medical Device Research Institute, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0003-4315-6665
Xuan LuoInstitute for NanoScale Science and Technology, College of Science and Engineering, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0002-8811-3143
Damian TohlAustralia-China Joint Research Centre on Personal Health Technologies, Medical Device Research Institute, Flinders University, Adelaide, SA 5042, Australia.
Anh Tran Tam PhamAustralia-China Joint Research Centre on Personal Health Technologies, Medical Device Research Institute, Flinders University, Adelaide, SA 5042, Australia.
Colin RastonInstitute for NanoScale Science and Technology, College of Science and Engineering, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0003-4753-0079
Youhong TangAustralia-China Joint Research Centre on Personal Health Technologies, Medical Device Research Institute, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0003-2718-544X
Flinders University · AU

Funding

Australia-China Joint Research Centre for Personal Health Technologies Australia-China Joint Research FundAustralian Government Research Training Program Scholarship Qi HuFlinders University Research Investment Fund 2022 Xuan Luo
6 · The paper itself

Abstract

Hydrogels have various promising prospects as a successful platform for detecting biomarkers, and human serum albumin (HSA) is an important biomarker in the diagnosis of kidney diseases. However, the difficult-to-control passive diffusion kinetics of hydrogels is a major factor affecting detection performance. This study focuses on using hydrogels embedded with aggregation-induced emission (AIE) fluorescent probe TC426 to detect HSA in real time. The vortex fluidic device (VFD) technology is used as a rotation strategy to control the reaction kinetics and micromixing during measurement. The results show that the introduction of VFD could significantly accelerate its fluorescence response and effectively improve the diffusion coefficient, while VFD processing could regulate passive diffusion into active diffusion, offering a new method for future sensing research.

Indexed as

Fluorescent DyesSerum Albumin, HumanHumansHydrogelsSpectrometry, FluorescenceFluorescent DyesHydrogelsSerum Albumin, Humanaggregation-induced emissionfluorescence biosensorhuman serum albuminhydrogel filmsvortex fluidic device

Identifiers

PMID37050007
PMCPMC10096627
OpenAlexW4362610882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.