Evidence map›Paper›PMID 37049986›Full record

ArticleMolecules (Basel, Switzerland)2023

Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from

Ngoc-Thao-Hien Le, Steven De Jonghe, Kristien Erven, Tom Vermeyen, Aliou M Baldé, Wouter A Herrebout, Johan Neyts, Christophe Pannecouque, Luc Pieters, Emmy Tuenter

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ngoc-Thao-Hien LeNatural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.ORCID 0000-0002-8834-593X
Steven De JongheLaboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.ORCID 0000-0002-3872-6558
Kristien ErvenLaboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Tom VermeyenDepartment of Chemistry, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium.ORCID 0000-0001-6049-2623
Aliou M BaldéDepartment of Pharmacy, University Gamal Abdel Nasser of Conakry, Conakry 00224, Guinea.ORCID 0000-0001-8813-772X
Wouter A HerreboutDepartment of Chemistry, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium.ORCID 0000-0002-3167-8944
Johan NeytsLaboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.ORCID 0000-0002-0033-7514
Christophe PannecouqueLaboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Luc PietersNatural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.ORCID 0000-0002-8288-4254
Emmy TuenterNatural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.ORCID 0000-0003-3765-0341
University of Antwerp · BERega Institute for Medical Research · BEGamal Abdel Nasser University of Conakry · GN

Funding

Research Foundation - Flanders G014521N
6 · The paper itself

Abstract

The Amaryllidaceae species are well-known as a rich source of bioactive compounds in nature. Although

Indexed as

AmaryllidaceaeAmaryllidaceae AlkaloidsCOVID-19LiliaceaeIsoquinolinesPhenanthridinesAmaryllidaceae AlkaloidsIsoquinolineslycorinepancratistatinPhenanthridinespseudolycorineAmaryllidaceae alkaloidsDFT calculationgalanthamine-typeHymenocallis littoralislycorine-typeSARS-CoV-2

Identifiers

PMID37049986
PMCPMC10096449
OpenAlexW4362638725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.