Evidence map›Paper›PMID 37049913›Full record

ArticleMolecules (Basel, Switzerland)2023

Site-Selective Incorporation of a Functional Group into Lys175 in the Vicinity of the Active Site of Chymotrypsin by Using Peptidyl α-Aminoalkylphosphonate Diphenyl Ester-Derivatives.

Shin Ono, Masato Koga, Yuya Arimura, Takahiro Hatakeyama, Mai Kobayashi, Jun-Ichi Sagara, Takahiko Nakai, Yoshikazu Horino, Hirofumi Kuroda, Hiroshi Oyama and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Shin OnoApplied Chemistry, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Masato KogaApplied Chemistry, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Yuya ArimuraApplied Chemistry, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Takahiro HatakeyamaApplied Chemistry, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Mai KobayashiApplied Chemistry, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Jun-Ichi SagaraApplied Bioengineering, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Takahiko NakaiGraduate School of Science and Engineering, University of Toyama, Toyama 930-8555, Toyama, Japan.
Yoshikazu HorinoDepartment of Applied Chemistry and Bioscience, Chitose Institute of Science and Technology, Chitose 066-8655, Hokkaido, Japan.ORCID 0000-0002-8916-6298
Hirofumi KurodaDepartment of General Education, National Institute of Technology, Ishikawa College, Tsubata 929-0392, Ishikawa, Japan.
Hiroshi OyamaFaculty of Science and Engineering, Setsunan University, Hirakata 572-8508, Osaka, Japan.
Kazunari ArimaGraduate School of Science and Engineering, Kagoshima University, Kagoshima 890-0065, Kagoshima, Japan.
Kanazawa Institute of Technology · JPChitose Institute of Science and Technology · JPKagoshima University · JPNational Institute of Technology · JPSetsunan University · JPUniversity of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that Lys175 in the region of the active site of chymotrypsin (Csin) could be site-selectively modified by using an

Indexed as

ChymotrypsinTandem Mass SpectrometryBiphenyl CompoundsCatalytic DomainChromatography, LiquidbiphenylBiphenyl CompoundsChymotrypsinchymotrypsindansyl groupdiphenyl α-aminoalkylphosphonatesite-selective chemical modification

Identifiers

PMID37049913
PMCPMC10096113
OpenAlexW4362585233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.