Evidence map›Paper›PMID 37049905›Full record

ReviewMolecules (Basel, Switzerland)2023

Enantioselective Synthesis of Atropisomers by Oxidative Aromatization with Central-to-Axial Conversion of Chirality.

Clément Lemaitre, Stefania Perulli, Ophélie Quinonero, Cyril Bressy, Jean Rodriguez, Thierry Constantieux, Olga García Mancheño, Xavier Bugaut

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Clément LemaitreAix Marseille Univ, CNRS, Centrale Marseille, iSm2, 13397 Marseille, France.
Stefania PerulliOrganic Chemistry Institute, University of Münster, Corrensstraße 36/40, 48149 Münster, Germany.
Ophélie QuinoneroAix Marseille Univ, CNRS, Centrale Marseille, iSm2, 13397 Marseille, France.
Cyril BressyAix Marseille Univ, CNRS, Centrale Marseille, iSm2, 13397 Marseille, France.
Jean RodriguezAix Marseille Univ, CNRS, Centrale Marseille, iSm2, 13397 Marseille, France.
Thierry ConstantieuxAix Marseille Univ, CNRS, Centrale Marseille, iSm2, 13397 Marseille, France.
Olga García MancheñoOrganic Chemistry Institute, University of Münster, Corrensstraße 36/40, 48149 Münster, Germany.ORCID 0000-0002-7578-5418
Xavier BugautAix Marseille Univ, CNRS, Centrale Marseille, iSm2, 13397 Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atropisomers are fascinating objects of study by themselves for chemists but also find applications in various sub-fields of applied chemistry. Obtaining them in enantiopure form is far from being a solved challenge, and the past decades has seen a surge of methodological developments in that direction. Among these strategies, oxidative aromatization with central-to-axial conversion of chirality has gained increasing popularity. It consists of the oxidation of a cyclic non-aromatic precursors into the corresponding aromatic atropisomers. This review proposes a critical analysis of this research field by delineating it and discussing its historical background and its present state of the art to draw potential future development directions.

Indexed as

aromatic compoundsatropisomersconversion of chiralityenantioselectivityoxidation

Identifiers

PMID37049905
PMCPMC10095918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.