Evidence map›Paper›PMID 37049825›Full record

ArticleMolecules (Basel, Switzerland)2023

Taipan Natriuretic Peptides Are Potent and Selective Agonists for the Natriuretic Peptide Receptor A.

Simone Vink, Kalyana Bharati Akondi, Jean Jin, Kim Poth, Allan M Torres, Philip W Kuchel, Sandra L Burke, Geoffrey A Head, Paul F Alewood

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Simone VinkInstitute for Molecular Bioscience, The University of Queensland, St Lucia 4072, Australia.
Kalyana Bharati AkondiDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.
Jean JinInstitute for Molecular Bioscience, The University of Queensland, St Lucia 4072, Australia.
Kim PothInstitute for Molecular Bioscience, The University of Queensland, St Lucia 4072, Australia.
Allan M TorresNanoscale Organisation and Dynamics Group, Western Sydney University, Penrith 2759, Australia.
Philip W KuchelSchool of Life and Environmental Sciences, University of Sydney, Sydney 2006, Australia.ORCID 0000-0003-4100-7332
Sandra L BurkeBaker Heart and Diabetes Institute, Melbourne 3004, Australia.
Geoffrey A HeadBaker Heart and Diabetes Institute, Melbourne 3004, Australia.
Paul F AlewoodInstitute for Molecular Bioscience, The University of Queensland, St Lucia 4072, Australia.ORCID 0000-0001-7454-6522
The University of Queensland · AUBaker Heart and Diabetes Institute · AUThe University of Sydney · AUUniversity of Geneva · CHWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular ailments are a major cause of mortality where over 1.3 billion people suffer from hypertension leading to heart-disease related deaths. Snake venoms possess a broad repertoire of natriuretic peptides with therapeutic potential for treating hypertension, congestive heart failure, and related cardiovascular disease. We now describe several taipan (

Indexed as

HypertensionNatriuretic PeptidesAnimalsElapidaeHeartHumansRabbitsRatsReceptors, Atrial Natriuretic Factoratrial natriuretic factor receptor ANatriuretic PeptidesReceptors, Atrial Natriuretic FactorNMR structurepeptide stabilitypeptide synthesistaipan natriuretic peptideTNP pharmacology

Identifiers

PMID37049825
PMCPMC10095932
OpenAlexW4361276716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.