Evidence map›Paper›PMID 37049662›Full record

ArticleMolecules (Basel, Switzerland)2023

Integrated Approach for Synthetic Cathinone Drug Prioritization and Risk Assessment: In Silico Approach and Sub-Chronic Studies in

Ariana Pérez-Pereira, Ana Rita Carvalho, João Soares Carrola, Maria Elizabeth Tiritan, Cláudia Ribeiro

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ariana Pérez-PereiraTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.
Ana Rita CarvalhoTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.
João Soares CarrolaDepartment of Biology and Environment, University of Trás-os-Montes and Alto Douro (UTAD), CITAB, 5000-801 Vila Real, Portugal.
Maria Elizabeth TiritanTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0003-3320-730X
Cláudia RibeiroTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0001-7245-4552
Cooperativa de Ensino Superior Politécnico e Universitário · PTUniversity of Trás-os-Montes and Alto Douro · PTUniversidade do Porto · PT

Funding

Fundação para a Ciência e Tecnologia PTDC/CTA-AMB/6686/2020Fundação para a Ciência e Tecnologia UIDB/04423/2020Fundação para a Ciência e Tecnologia UIDP/04423/2020
6 · The paper itself

Abstract

Synthetic cathinones (SC) are drugs of abuse that have been reported in wastewaters and rivers raising concern about potential hazards to non-target organisms. In this work, 44 SC were selected for in silico studies, and a group of five emerging SC was prioritized for further in vivo ecotoxicity studies: buphedrone (BPD), 3,4-dimethylmethcathinone (3,4-DMMC), butylone (BTL), 3-methylmethcathinone (3-MMC), and 3,4-methylenedioxypyrovalerone (MDPV). In vivo short-term exposures were performed with the protozoan

Indexed as

Synthetic DrugsTetrahymena thermophilaWater Pollutants, ChemicalAnimalsDaphniaEcosystemPropiophenonesSynthetic Cathinone3,4-dimethylmethcathinonePropiophenonesSynthetic CathinoneSynthetic DrugsWater Pollutants, Chemicalenvironmental managementin silico predictionmicrocrustaceanprotozoanpsychoactive emergent contaminants

Identifiers

PMID37049662
PMCPMC10096003
OpenAlexW4360863503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.