Evidence map›Paper›PMID 37049657›Full record

ArticleMolecules (Basel, Switzerland)2023

Utilizing Contrast-Enhanced Ultrasonography with Phosphatidylserine Microbubbles to Detect Placental Inflammation in Rhesus Macaques.

Rachel C Wilson, Jamie O Lo, Gabriel Romero Jimenez, Jonathan R Lindner, Ov D Slayden, Victoria H J Roberts

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rachel C WilsonDivision of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Beaverton, OR 97006, USA.ORCID 0000-0002-7564-5917
Jamie O LoDepartment of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR 97239, USA.
Gabriel Romero JimenezDivision of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Jonathan R LindnerCardiovascular Division, University of Virginia Medical Center, Charlottesville, VA 22903, USA.
Ov D SlaydenDivision of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Beaverton, OR 97006, USA.ORCID 0000-0003-3748-8292
Victoria H J RobertsDivision of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Oregon National Primate Research Center · USOregon Health & Science University · USUniversity of Virginia Medical Center · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
PROJECT 4: ANDROGEN EXCESS IN ADIPOGENIC DYSFUNCTION IN PCOS WOMENP50HD071836 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI DUMESIC, DANIEL A · 2014 to 2021
$14.7M
Targeted CEU Imaging of Atherosclerosis and AngiogenesisR01HL078610 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LINDNER, JONATHAN R · 2004 to 2022
$6.8M
Advanced Non-invasive Imaging in the Investigation of Aortic Stenosis PathobiologyR01HL165422 · NHLBI · UNIVERSITY OF VIRGINIA · PI Jonathan R Lindner · 2022 to 2026
$3.5M
Monitoring the progression of endometriosis using PET/CT imagingF32HD107809 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILSON, RACHEL CATHARINE · 2022 to 2023
$86k
NHLBI NIH HHS R01 HL078610NHLBI NIH HHS R01 HL165422NICHD NIH HHS F32 HD107809NICHD NIH HHS P50 HD071836NIH HHS P50 HD071836, P51 OD011092, R01 HL078610, R01 HL165422, R01 HL130043, F32 HD 107809NIH HHS P51 OD011092
6 · The paper itself

Abstract

The ability to comprehensively monitor physiological and detect pathophysiologic processes early during pregnancy can reduce maternal and fetal morbidity and mortality. Contrast-enhanced ultrasound (CEUS) is a non-invasive imaging technology that utilizes the acoustic detection of microbubbles to examine vascular spaces. Furthermore, microbubbles conjugated to specific compounds can focus studies on precise physiological pathways. We hypothesized that CEUS with phosphatidylserine microbubbles (MB-PS) could be employed to monitor placental inflammation. We tested this hypothesis in rhesus macaques (

Indexed as

PhosphatidylserinesPlacentaAnimalsContrast MediaFemaleHumansInflammationMacaca mulattaMicrobubblesPregnancyTestosteroneUltrasonographyContrast MediaPhosphatidylserinesTestosteroneangiopoietinscontrast agentintervillous spacein vivo imagingpregnancyselectin psyncytiotrophoblast

Identifiers

PMID37049657
PMCPMC10096139
OpenAlexW4360865068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.