Evidence map›Paper›PMID 37049616›Full record

ArticleNutrients2023

Effects of Immunonutrition on Cancer Patients Undergoing Surgery: A Scoping Review.

Katherine García-Malpartida, Carmen Aragón-Valera, Francisco Botella-Romero, María Julia Ocón-Bretón, Juan J López-Gómez

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katherine García-MalpartidaEndocrinology and Nutrition Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain.ORCID 0000-0001-7091-421X
Carmen Aragón-ValeraHospital Universitario Fundación Jiménez Díaz, 28040 Madrid, Spain.
Francisco Botella-RomeroCoordinador Comité Gestor Área de Nutrición, Sociedad Española Endocrinología y Nutrición (SEEN); 28001 Madrid, Spain.ORCID 0000-0001-9947-0974
María Julia Ocón-BretónNutrition Department, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, Spain.
Juan J López-GómezEndocrinology and Nutrition Department, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, Spain.ORCID 0000-0003-3144-343X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is a large body of evidence about immunonutrition formulas; however, there are still doubts about their usefulness in routine clinical practice as compared with standard formulas. In the age of personalized medicine, new studies appear every year regarding several types of patients; therefore, an updated point of view on these formulas is necessary.

methodsThe Embase database was searched from 2016 to 14 March 2022. Our criteria were articles published in English and Spanish. The evidence quality was evaluated using GRADEpro, and the review was developed according to the PRISMA statement.

resultsIn this review, a total of 65 unique records were retrieved; however, 36 articles did not meet the inclusion criteria and were thus excluded. In total, 29 articles were included in the final analysis. In the last few years, many meta-analyses have attempted to identify additional existing studies of surgical patients with certain pathologies, mainly oncological patients. Immunonutrition prior to oncological surgery was shown to cause a decrease in inflammatory markers in most of the studies, and the main clinical events that changed were the infectious complications after surgery. The length of stay and mortality data are controversial due to the specific risk factors associated with these events.

conclusionsThe use of immunonutrition in patients who have undergone oncological surgery decreases the levels of inflammatory markers and infectious postoperative complications in almost all localizations. However, more studies are needed to assess the use of immunonutrition based on Enhanced Recovery After Surgery (ERAS) protocols.

Indexed as

NeoplasmsPostoperative ComplicationsFood, FormulatedHumansImmunonutrition DietLength of StayRisk Factorscancercomplicationsimmunonutritionmortalityoncological surgery

Identifiers

PMID37049616
PMCPMC10096769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.