Evidence map›Paper›PMID 37049550›Full record

ReviewNutrients2023

Magnesium in Kidney Function and Disease-Implications for Aging and Sex-A Narrative Review.

María Del Carmen Macías Ruiz, Lorena Cuenca Bermejo, Nicola Veronese, Emiliano Fernández Villalba, Ana María González Cuello, Karolina Kublickiene, Valeria Raparelli, Colleen M Norris, Alexandra Kautzky-Willer, Louise Pilote and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 5 countries.

María Del Carmen Macías RuizClinical and Experimental Neuroscience (NiCE), Institute for Aging Research, Biomedical Institute of Murcia (IMIB-Pascual Parrilla), School of Medicine, Campus Mare Nostrum, UniWell, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0001-8556-6262
Lorena Cuenca BermejoClinical and Experimental Neuroscience (NiCE), Institute for Aging Research, Biomedical Institute of Murcia (IMIB-Pascual Parrilla), School of Medicine, Campus Mare Nostrum, UniWell, University of Murcia, 30100 Murcia, Spain.
Nicola VeroneseGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, Italy.ORCID 0000-0002-9328-289X
Emiliano Fernández VillalbaClinical and Experimental Neuroscience (NiCE), Institute for Aging Research, Biomedical Institute of Murcia (IMIB-Pascual Parrilla), School of Medicine, Campus Mare Nostrum, UniWell, University of Murcia, 30100 Murcia, Spain.
Ana María González CuelloClinical and Experimental Neuroscience (NiCE), Institute for Aging Research, Biomedical Institute of Murcia (IMIB-Pascual Parrilla), School of Medicine, Campus Mare Nostrum, UniWell, University of Murcia, 30100 Murcia, Spain.
Karolina KublickieneDepartment of Renal Medicine, Institution for Clinical Science, Intervention and Technology, Karolinska Institute, 17177 Stockholm, Sweden.ORCID 0000-0002-4841-6836
Valeria RaparelliDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-2100-5682
Colleen M NorrisFaculty of Nursing, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-6793-9333
Alexandra Kautzky-WillerDivision of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-3520-4105
Louise PiloteResearch Institute of McGill University Health Centre, Divisions of General Internal Medicine and Clinical Epidemiology, McGill University, Montreal, QC H4A 3J1, Canada.
Mario BarbagalloGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, Italy.ORCID 0000-0002-1349-6530
Ligia DominguezGeriatric Unit, Department of Medicine, University of Palermo, 90100 Palermo, Italy.
María Trinidad HerreroClinical and Experimental Neuroscience (NiCE), Institute for Aging Research, Biomedical Institute of Murcia (IMIB-Pascual Parrilla), School of Medicine, Campus Mare Nostrum, UniWell, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0003-4953-1446
GOING-FWD Consortium
Universidad de Murcia · ESUniversity of Palermo · ITAlberta Health Services · CAKarolinska Institutet · SEMcGill University Health Centre · CAMedical University of Vienna · ATUniversità degli Studi di Enna Kore · ITUniversity of Ferrara · IT

Funding

Austrian Science Fund [FWF, I 4209]CIHR [GNP-161904]GENDER-NET Plus ERA-NET Initiative [Project Ref. no.: GNP-78]"La Caixa" Foundation [ID 100010434] LCF/PR/DE18/52010001Swedish Research Council [2018-00932]Universidad de Murcia UM/R714/2021
6 · The paper itself

Abstract

Magnesium (Mg) has a vital role in the human body, and the kidney is a key organ in the metabolism and excretion of this cation. The objective of this work is to compile the available evidence regarding the role that Mg plays in health and disease, with a special focus on the elderly population with chronic kidney disease (CKD) and the eventual sex differences. A narrative review was carried out by executing an exhaustive search in the PubMed, Scopus, and Cochrane databases. Ten studies were found in which the role of Mg and sex was evaluated in elderly patients with CKD in the last 10 years (2012-2022). The progression of CKD leads to alterations in mineral metabolism, which worsen as the disease progresses. Mg can be used as a coadjuvant in the treatment of CKD patients to improve glomerular filtration, but its use in clinical applications needs to be further characterized. In conclusion, there's a need for well-designed prospective clinical trials to advise and standardize Mg supplementation in daily clinical practice, taking age and sex into consideration.

Indexed as

MagnesiumRenal Insufficiency, ChronicAgedAgingDisease ProgressionFemaleGlomerular Filtration RateHumansKidneyMaleProspective StudiesMagnesiumchronic kidney diseaseelderlykidney functionmagnesiumsex

Identifiers

PMID37049550
PMCPMC10097335
OpenAlexW4362468562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.