Evidence map›Paper›PMID 37049467›Full record

ArticleNutrients2023

Do Poor Diet and Lifestyle Behaviors Modify the Genetic Susceptibility to Impulsivity in the General Population?

Tian Xie, Lizanne J S Schweren, Henrik Larsson, Lin Li, Ebba Du Rietz, Jan Haavik, Lifelines Cohort Study, Liv Grimstvedt Kvalvik, Berit Skretting Solberg, Kari Klungsøyr and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Tian XieInterdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Department of Psychiatry, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.ORCID 0000-0003-2442-7941
Lizanne J S SchwerenInterdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Department of Psychiatry, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.ORCID 0000-0001-6018-5316
Henrik LarssonSchool of Medical Sciences, Örebro University, 70172 Örebro, Sweden.
Lin LiDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17165 Stockholm, Sweden.ORCID 0000-0002-7946-4574
Ebba Du RietzDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17165 Stockholm, Sweden.
Jan HaavikDepartment of Biomedicine, University of Bergen, 5020 Bergen, Norway.ORCID 0000-0001-7865-2808
Lifelines Cohort Study
Liv Grimstvedt KvalvikDepartment of Global Public Health and Primary Care, University of Bergen, 5020 Bergen, Norway.ORCID 0000-0001-6520-9057
Berit Skretting SolbergDepartment of Biomedicine, University of Bergen, 5020 Bergen, Norway.
Kari KlungsøyrDepartment of Global Public Health and Primary Care, University of Bergen, 5020 Bergen, Norway.
Harold SniederDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.ORCID 0000-0003-1949-2298
Catharina A HartmanInterdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Department of Psychiatry, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.
University Medical Center Groningen · NLKarolinska Institutet · SEBetanien Hospital · NOHaukeland University Hospital · NONorwegian Institute of Public Health · NOÖrebro University · SEUniversity of Bergen · NO

Funding

European Union's Horizon 2020 Research and Innovation Program 728018
6 · The paper itself

Abstract

The present study investigated whether an unhealthy diet and other lifestyle behaviors may modify the genetic susceptibility to impulsivity. A total of 33,047 participants (mean age = 42.1 years, 59.8% females) from the Dutch Lifelines cohort were included. Each diet index and other lifestyle behaviors were tested for their interactions on the effect on the attention-deficit/hyperactivity disorder (ADHD) polygenic risk score (PRS) on impulsivity using a linear regression model with adjustment for covariates. The ADHD PRS was significantly associated with impulsivity (B = 0.03 (95% CI: 0.02, 0.04);

Indexed as

Attention Deficit Disorder with HyperactivityGenetic Predisposition to DiseaseAdultDietFemaleHumansImpulsive BehaviorLife StyleMaleRisk Factorsdietary habitsdiet-gene interactiongenetic susceptibilityimpulsivitylifestyle behaviors

Identifiers

PMID37049467
PMCPMC10096670
OpenAlexW4361224000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.