Evidence map›Paper›PMID 37049416›Full record

ArticleNutrients2023

A Low Daily Intake of Simple Sugars in the Diet Is Associated with Improved Liver Function in Cirrhotic Liver Transplant Candidates.

Simona Parisse, Sara Carnevale, Francesca Di Bartolomeo, Edoardo Poli, Francesca Miceli, Flaminia Ferri, Monica Mischitelli, Bianca Rocco, Quirino Lai, Pierleone Lucatelli and 7 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Simona ParisseDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Sara CarnevaleBelcolle Hospital, 01100 Viterbo, Italy.
Francesca Di BartolomeoDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Edoardo PoliCentre Hépato-Biliaire, Hôpital Paul Brousse, AP-HP, 94800 Villejuif, France.
Francesca MiceliDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-8303-4000
Flaminia FerriDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-8553-5589
Monica MischitelliDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Bianca RoccoDepartment of Radiological, Oncological and Anatomopathological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-5073-2846
Quirino LaiGeneral Surgery and Organ Transplantation Unit, Department of Surgery, Sapienza University of Rome, 00161 Rome, Italy.
Pierleone LucatelliDepartment of Radiological, Oncological and Anatomopathological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-7448-1404
Mario CoronaDepartment of Radiological, Oncological and Anatomopathological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Gianluca MenniniGeneral Surgery and Organ Transplantation Unit, Department of Surgery, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-6412-6863
Adriano De SantisDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Massimo RossiGeneral Surgery and Organ Transplantation Unit, Department of Surgery, Sapienza University of Rome, 00161 Rome, Italy.
Maurizio MuscaritoliDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Alfredo CantaforaDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Stefano Ginanni CorradiniDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0839-1961
Sapienza University of Rome · ITAssistance Publique – Hôpitaux de Paris · FROspedale di Belcolle · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: We investigated, for the first time, whether dietary simple sugar intake affects MELD score changes over time in a cohort of cirrhotic liver transplant candidates. (2) Methods: the MELD score, dietary habits using a 3-day food diary, and visceral adipose tissue index (VATI) measured with CT scan were assessed in 80 consecutive outpatient cirrhotic patients at baseline, after counseling to follow current nutritional guidelines. The MELD score was reassessed after six months and the DELTA-MELD was calculated as the MELD at the second assessment minus the MELD at baseline. (3) Results: Compared with the baseline, the MELD score of cirrhotic patients at the end of the study was decreased, stable, or increased in 36%, 8% and 56% of patients, respectively. In separate multiple linear regression models, DELTA-MELD was positively and independently correlated with the daily intake of simple sugars expressed in g/kg body weight (

Indexed as

Liver TransplantationDietHumansLiver CirrhosisMonosaccharidesPrognosisSeverity of Illness IndexMonosaccharidescirrhosiscirrhotic dietDELTA-MELDliver transplantsimple sugarsvisceral adipose tissue

Identifiers

PMID37049416
PMCPMC10097197
OpenAlexW4360858165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.