Evidence map›Paper›PMID 37049393›Full record

ArticleNutrients2023

Crosstalk between Gut Microbiota and Epigenetic Markers in Obesity Development: Relationship between

Francisca Salas-Perez, Taís Silveira Assmann, Omar Ramos-Lopez, J Alfredo Martínez, Jose Ignacio Riezu-Boj, Fermín I Milagro

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Francisca Salas-PerezHealth Sciences Institute, Universidad de O'Higgins, Rancagua 2820000, Chile.
Taís Silveira AssmannGraduate Program in Medical Sciences, Endocrinology, Department of Internal Medicine, Faculty of Medicine, Federal University of do Rio Grande do Sul, Porto Alegre 90035-003, Brazil.ORCID 0000-0001-9114-8243
Omar Ramos-LopezMedicine and Psychology School, Autonomous University of Baja California, Tijuana 22390, Mexico.ORCID 0000-0002-2505-1555
J Alfredo MartínezCenter for Nutrition Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-5218-6941
Jose Ignacio Riezu-BojCenter for Nutrition Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-1885-8457
Fermín I MilagroCenter for Nutrition Research, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3228-9916
Instituto de Salud Carlos III · ESNavarre Institute of Health Research · ESUniversidad Autónoma de Baja California · MXUniversidade Federal do Rio Grande do Sul · BRUniversity of O'Higgins · CL

Funding

CIBERobn CB12/03/30002Government of Navarra Microbiota-PI035Government of Navarra Nutribiota-0011-1411-2018-000040Government of Navarra Obekit-PT024PRODEP-Mexico program UABC-PTC-796
6 · The paper itself

Abstract

Changes in gut microbiota composition and in epigenetic mechanisms have been proposed to play important roles in energy homeostasis, and the onset and development of obesity. However, the crosstalk between epigenetic markers and the gut microbiome in obesity remains unclear. The main objective of this study was to establish a link between the gut microbiota and DNA methylation patterns in subjects with obesity by identifying differentially methylated DNA regions (DMRs) that could be potentially regulated by the gut microbiota. DNA methylation and bacterial DNA sequencing analysis were performed on 342 subjects with a BMI between 18 and 40 kg/m

Indexed as

Gastrointestinal MicrobiomeBody Mass IndexDNADNA MethylationDNA Repair EnzymesEpigenesis, GeneticHumansHydrolasesObesityRuminococcusDNADNA Repair EnzymesHydrolasesMACROD2 protein, humanDMRMACROD2methylationmicrobiotaobesity

Identifiers

PMID37049393
PMCPMC10097304
OpenAlexW4360616326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.