Evidence map›Paper›PMID 37049340›Full record

ReviewNanomaterials (Basel, Switzerland)2023

Nanotechnology-Based Diagnostics for Diseases Prevalent in Developing Countries: Current Advances in Point-of-Care Tests.

Lungile Nomcebo Thwala, Sphumelele Colin Ndlovu, Kelvin Tafadzwa Mpofu, Masixole Yvonne Lugongolo, Patience Mthunzi-Kufa

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lungile Nomcebo ThwalaNational Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa.ORCID 0000-0002-0687-3908
Sphumelele Colin NdlovuNational Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa.
Kelvin Tafadzwa MpofuNational Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa.
Masixole Yvonne LugongoloNational Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa.
Patience Mthunzi-KufaNational Laser Centre, Council for Scientific and Industrial Research, P.O. Box 395, Pretoria 0001, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The introduction of point-of-care testing (POCT) has revolutionized medical testing by allowing for simple tests to be conducted near the patient's care point, rather than being confined to a medical laboratory. This has been especially beneficial for developing countries with limited infrastructure, where testing often involves sending specimens off-site and waiting for hours or days for results. However, the development of POCT devices has been challenging, with simplicity, accuracy, and cost-effectiveness being key factors in making these tests feasible. Nanotechnology has played a crucial role in achieving this goal, by not only making the tests possible but also masking their complexity. In this article, recent developments in POCT devices that benefit from nanotechnology are discussed. Microfluidics and lab-on-a-chip technologies are highlighted as major drivers of point-of-care testing, particularly in infectious disease diagnosis. These technologies enable various bioassays to be used at the point of care. The article also addresses the challenges faced by these technological advances and interesting future trends. The benefits of point-of-care testing are significant, especially in developing countries where medical care is shifting towards prevention, early detection, and managing chronic conditions. Infectious disease tests at the point of care in low-income countries can lead to prompt treatment, preventing infections from spreading.

Indexed as

diagnosticsinfectiousnanoparticlesnanotechnologynon-infectiouspoint of care

Identifiers

PMID37049340
PMCPMC10096522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.