ArticleJournal of clinical medicine2023
Reducing Post-Operative Alveolo-Pleural Fistula by Applying PGA-Sheets (Neoveil) after Major Lung Resection: A Historical Case-Control Study.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 6 citations in OpenAlex.
- Air leaks management using polymeric hydrogel matrix after thoracoscopic lung segmentectomy: a single-center prospective randomized trial with a cost-effective analysis.Updates in surgery · 2026Trial
- Systematic or On-Demand Sealant Use in Minimally Invasive Lung Surgery: A Matched Comparison.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Efficacy of bioabsorbable staple line reinforcement in reducing air leakage following pulmonary resection: a cadaveric study.Journal of thoracic disease · 2026Article
- Blood loss and prolonged air leak reduction by applying TenaTacGeneral thoracic and cardiovascular surgery · 2026Article
- Polyglycolic Acid Aerostatic Patch for Air Leak Management: Results from a Decade of Pulmonary Resections Using Propensity-Score Weighting.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Modified free pericardial fat pledget technique for intraoperative air leak management in robotic-assisted thoracic surgery.Journal of thoracic disease · 2025Article
- Predictors of intraoperative and postoperative air leakage in anatomical pulmonary resection.Surgery today · 2025Article
- Evaluating air leakage from staple line reinforcements in anatomical pulmonary resection (AIRSTOP): a prospective randomized controlled trial protocol.General thoracic and cardiovascular surgery · 2025Article
- Mastering the maze: navigating prolonged air leak in thoracic surgery.Journal of visualized surgery · 2024Review
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Authors and funding
17 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alveolo-pleural fistula remains a serious post-operative complication in lung cancer patients after surgery, which is associated with prolonged hospital stay and higher healthcare costs. The aim of this study is to evaluate the efficacy of a polyglycol acid (PGA)-sheet known as Neoveil in preventing post-operative air-leak in cases of detected intra-operative air-leak after lung resection. Between 11/2021 and 7/2022, a total of 329 non-small cell lung cancer (NSCLC) patients were surgically treated in two institutions. Major lung resections were performed in 251 cases. Among them, 44 patients with significant intra-operative air-leak at surgery were treated by reinforcing staple lines with Neoveil (study group). On the other hand, a historical group (selected by propensity score matched analysis) consisting of 44 lung cancer patients with significant intra-operative air leak treated by methods other than the application of sealant patches were considered as the control group. The presence of prolonged air-leak (primary endpoint), pleural drainage duration, hospital stay, and post-operative complication rates were evaluated. The results showed that prolonged air-leak (>5 days after surgery) was not observed in study group, while this event occurred in four patients (9.1%) in the control group. Additionally, a substantial reduction (despite not statistically significant) in the chest tube removal was noted in the study group with respect to the control group (3.5 vs. 4.5,
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