Evidence map›Paper›PMID 37048775›Full record

ArticleJournal of clinical medicine2023

Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis.

Greg Gilles, Arjun Vohra, Dagoberto Robles, Mihra S Taljanovic, Erin L Ashbeck, Chelsea Caruso, Jeffrey Duryea, Edward J Bedrick, Ali Guermazi, C Kent Kwoh

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Greg GillesUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA.ORCID 0009-0005-2577-2116
Arjun VohraUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Dagoberto RoblesUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Mihra S TaljanovicUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Erin L AshbeckUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Chelsea CarusoUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
Jeffrey DuryeaDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Edward J BedrickDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA.
Ali GuermaziVA Boston Healthcare System, West Roxbury, Boston, MA 02132, USA.ORCID 0000-0002-9374-8266
C Kent KwohUniversity of Arizona Arthritis Center, University of Arizona College of Medicine, Tucson, AZ 85724, USA.ORCID 0000-0001-5937-550X
University of Arizona · USBoston University · USBrigham and Women's Hospital · US

Funding

Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage LossR01AR071409 · NIAMS · UNIVERSITY OF ARIZONA · PI DURYEA, JEFFREY W, GUERMAZI, ALI · 2017 to 2020
$2.2M
NIAMS NIH HHS R01 AR071409NIH HHS AR071409
6 · The paper itself

Abstract

Effusion-synovitis (ES) is recognized as a component of osteoarthritis, creating a need for rapid methods to assess ES on MRI. We describe the development and reliability of an efficient single-slice semi-automated quantitative approach to measure ES. We used two samples from the Osteoarthritis Initiative (OAI): 50 randomly selected OAI participants with radiographic osteoarthritis (i.e., Kellgren-Lawrence (KL) grade 2 or 3) and a subset from the Foundation for the National Institutes of Health Osteoarthritis Biomarker study. An experienced musculoskeletal radiologist trained four non-expert readers to use custom semi-automated software to measure ES on a single axial slice and then read scans blinded to prior assessments. The estimated intraclass correlation coefficient (ICC) for intra-reader reliability of the single-slice ES method in the KL 2-3 sample was 0.96 (95% CI: 0.93, 0.97), and for inter-reader reliability, the ICC was 0.90 (95% CI: 0.87, 0.95). The intra-reader mean absolute difference (MAD) was 35 mm

Indexed as

biomarkerseffusioninflammationkneeMRIosteoarthritisquantitative imagingsemi-automatedsynovitis

Identifiers

PMID37048775
PMCPMC10095125
OpenAlexW4362557700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.