Evidence map›Paper›PMID 37048758›Full record

ArticleJournal of clinical medicine2023

Sex, Age, and Comorbidities Are Associated with SARS-CoV-2 Infection, COVID-19 Severity, and Fatal Outcome in a Mexican Population: A Retrospective Multi-Hospital Study.

Maria Elena Camacho Moll, Viviana Leticia Mata Tijerina, Beatriz Silva Ramírez, Katia Peñuelas Urquides, Laura Adiene González Escalante, Brenda Leticia Escobedo Guajardo, Jorge Eleazar Cruz Luna, Roberto Corrales Pérez, Salvador Gómez García, Mario Bermúdez de León

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Maria Elena Camacho MollLaboratory of Molecular Biology, Northeast Biomedical Research Centre, Mexican Social Security Institute, Monterrey 64720, Mexico.
Viviana Leticia Mata TijerinaLaboratory of Immunogenetics, Northeast Biomedical Research Centre, Mexican Social Security Institute, Monterrey 64720, Mexico.ORCID 0000-0001-5038-5496
Beatriz Silva RamírezLaboratory of Immunogenetics, Northeast Biomedical Research Centre, Mexican Social Security Institute, Monterrey 64720, Mexico.ORCID 0000-0001-6262-7843
Katia Peñuelas UrquidesLaboratory of Molecular Microbiology, Northeast Biomedical Research Centre, Mexican Social Security Institute, Monterrey 64720, Mexico.
Laura Adiene González EscalanteLaboratory of Molecular Microbiology, Northeast Biomedical Research Centre, Mexican Social Security Institute, Monterrey 64720, Mexico.
Brenda Leticia Escobedo GuajardoLaboratory of Molecular Research of Diseases, Northeast Biomedical Research Centre, Mexican Social Security Institute, Monterrey 64720, Mexico.ORCID 0000-0002-9184-0296
Jorge Eleazar Cruz LunaMedical Epidemiological Assistance Coordination of the State of Nuevo León, Mexican Social Security Institute, Monterrey 64000, Mexico.
Roberto Corrales PérezMedical Epidemiological Assistance Coordination of the State of Nuevo León, Mexican Social Security Institute, Monterrey 64000, Mexico.
Salvador Gómez GarcíaMedical Epidemiological Assistance Coordination of the State of Nuevo León, Mexican Social Security Institute, Monterrey 64000, Mexico.
Mario Bermúdez de LeónLaboratory of Molecular Biology, Northeast Biomedical Research Centre, Mexican Social Security Institute, Monterrey 64720, Mexico.ORCID 0000-0002-0993-2969
Mexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People with comorbidities and the male sex are at a higher risk of developing severe COVID-19. In the present study, we aim to investigate the associated factors for infection, severity, and death due to COVID-19 in a population from Nuevo León, México. Epidemiological COVID-19 data were collected from 65 hospitals from December 2020 to May 2022. A total of 75,232 cases were compiled from which 25,722 cases were positive for SARS-CoV-2. Male sex, older age, diabetes, obesity, and hypertension were associated with infection. In addition to the above-mentioned factors, renal disease, cardiovascular disease, and immunosuppression were found to be associated with increased COVID-19 severity. These factors, as well as neurological diseases, are also associated with death due to COVID-19. When comparing the different variants of SARs-CoV-2, the variant B1.1.519 increased the probability of death by 2.23 times compared to the AY.20 variant. Male sex, older age, diabetes, obesity, and hypertension are associated with SARS-CoV-2 infection, severity, and death. Along with the aforementioned comorbidities, renal disease, cardiovascular disease, and immunosuppression are also associated with severity and death. Another factor associated with death is the presence of neurological disease. The SARS-CoV-2 B1.1.519 variant increases the odds of death compared to the SARS-CoV-2 AY.20 variant.

Indexed as

associationCOVID-19deathMexicoSARS-CoV-2severity

Identifiers

PMID37048758
PMCPMC10095205
OpenAlexW4362559278

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.