ReviewJournal of clinical medicine2023
Mechanical Insufflation-Exsufflation: Considerations for Improving Clinical Practice.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07722260 (Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients), which is not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients
Who cites it
18 citing papers in PubMed.
- The role of the respiratory physiotherapist in the management of Duchenne muscular dystrophy.Breathe (Sheffield, England) · 2026Review
- Consideration for the appropriate use of antimicrobials in long-term care wards.Infection prevention in practice · 2026Article
- Transition from ICU to home care with long-term invasive ventilation using a single-limb BiPAP circuit.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026Article
- Haemoperitoneum in the setting of therapeutic anticoagulation and manual assisted cough for a patient with an acute cervical spinal cord injury and pulmonary embolus: a case report.Spinal cord series and cases · 2025Article
- Perioperative Anesthetic Management in Pediatric Scoliosis Surgery: A Narrative Review with Focus on Neuromuscular Disorders.Children (Basel, Switzerland) · 2025Review
- Managing Cough in Pediatric Neuromuscular Disorders: Lung Function and Care Strategies.Children (Basel, Switzerland) · 2025Review
- Exploring mechanisms of behavior change for healthcare professionals in cough and secretion management in ALS.Neurodegenerative disease management · 2025Article
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- Article
- Mechanical insufflation-exsufflation use in neuromuscular disease: a single centre cohort study.BMJ open respiratory research · 2025Observational
- Synergistic Effect of Manually Assisted Cough During Mechanical Insufflation-Exsufflation in Patients With Spinal Cord Injury.Respiratory care · 2024Article
- Waves of Precision: A Practical Guide for Reviewing New Tools to Evaluate Mechanical In-Exsufflation Efficacy in Neuromuscular Disorders.Journal of clinical medicine · 2024Review
- Pilot observational cohort study to determine whether waveform and flow traces from mechanical insufflation-exsufflation (MI-E) can be used to identify laryngeal responses to MI-E and thus optimise treatment algorithms in neuromuscular patients in a tertiary centre: a protocol description.BMJ open respiratory research · 2024Article
- Hypotussic cough in persons with dysphagia: biobehavioral interventions and pathways to clinical implementation.Frontiers in rehabilitation sciences · 2024Review
- Management of Critically Ill Patients With Spinal Muscular Atrophy Admitted With Acute Respiratory Failure: The Authors' Reply.Respiratory care · 2023Article
- Non-Invasive Respiratory Support: How to Get It Right in Clinical Medicine.Journal of clinical medicine · 2023Article
- Article
- Equity, guidelines, and respiratory devices: Call to action for the Canadian health care system.Canadian family physician Medecin de famille canadienArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The provision of mechanical insufflation-exsufflation (MI-E) devices to enhance cough efficacy is increasing. Typically, MI-E devices are used to augment cough in patients with neuromuscular disorders but also in patients who are weak in an acute care setting. Despite a growing evidence base for the use of these devices, there are barriers to the provision of MI-E, including clinician lack of knowledge and confidence. Enhancing clinician education and confidence is key. Individualized or protocolized approaches can be used to initiate MI-E. Evaluation of MI-E efficacy is critical. One method to evaluate effectiveness of MI-E is the MI-E-assisted cough peak flow (CPF). However, this should always be considered alongside other factors discussed in this review. The purpose of this review is to increase the theoretical understanding of the provision and evaluation of MI-E and provide insight into how this knowledge can be applied into clinical practice. Approaches to initiation and titration can be selected based on the clinical situation, patient diagnosis (including and beyond neuromuscular disorders), and clinician's confidence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.