Evidence map›Paper›PMID 37048701›Full record

ArticleJournal of clinical medicine2023

Plasma Levels of Metalloproteinase 3 (MMP-3) and Metalloproteinase 7 (MMP-7) as New Candidates for Tumor Biomarkers in Diagnostic of Breast Cancer Patients.

Paweł Ławicki, Paweł Malinowski, Joanna Motyka, Michał Ławicki, Aleksandra Kicman, Monika Kulesza, Ewa Gacuta, Tomasz Guszczyn, Marcin Januszkiewicz, Monika Zbucka-Krętowska and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Paweł ŁawickiDepartment of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0003-4377-085X
Paweł MalinowskiDepartment of Oncological Surgery, Bialystok Oncology Center, 15-276 Bialystok, Poland.
Joanna MotykaDepartment of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0003-1815-2427
Michał ŁawickiDepartment of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, 15-269 Bialystok, Poland.
Aleksandra KicmanDepartment of Aesthetic Medicine, Medical University of Bialystok, 15-267 Bialystok, Poland.
Monika KuleszaDepartment of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, 15-269 Bialystok, Poland.
Ewa GacutaDepartment of Perinatology, University Clinical Hospital of Bialystok, 15-276 Bialystok, Poland.
Tomasz GuszczynDepartment of Pediatric Orthopaedics and Traumatology, Medical University of Bialystok, 15-089 Bialystok, Poland.
Marcin JanuszkiewiczDepartment of Oncological Surgery, Bialystok Oncology Center, 15-276 Bialystok, Poland.
Monika Zbucka-KrętowskaDepartment of Gynecological Endocrinology and Adolescent Gynecology, Medical University of Bialystok, 15-276 Bialystok, Poland.
Sławomir ŁawickiDepartment of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0001-6747-2123
Medical University of Białystok · PLUniversity Clinical Hospital In Bialystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs) are a group of enzymes that mediate both physiological and pathological processes such as carcinogenesis. The role of matrix metalloproteinase-3 (MMP-3) and (MMP-7) in the pathogenesis of breast cancer (BC) has been demonstrated, suggesting that they may be considered as potential markers of this condition. The aim of this study was to assess plasma concentrations and diagnostic utility of MMP-3 and MMP-7 in 100 patients with early-stage breast cancer with Luminal A subtype or Luminal B HER-negative subtype, before and after surgical treatment, and in the following control groups: patients with a benign tumor (

Indexed as

breast cancerca 15-3fibroadenomaluminal a subtypeluminal b her2-negative subtypemmp-3mmp-7

Identifiers

PMID37048701
PMCPMC10094779
OpenAlexW4362467418

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.