Evidence map›Paper›PMID 37048610›Full record

ArticleJournal of clinical medicine2023

Long-Term Effect of SARS-CoV-2 Infection on the Retinal and Choroidal Microvasculature.

Magdalena Kal, Mateusz Winiarczyk, Dorota Zarębska-Michaluk, Dominik Odrobina, Elżbieta Cieśla, Bernadetta Płatkowska-Adamska, Michał Biskup, Paweł Pabjan, Stanisław Głuszek, Jerzy Mackiewicz

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Magdalena KalCollegium Medicum, Jan Kochanowski University of Kielce, 25-369 Kielce, Poland.
Mateusz WiniarczykDepartment of Vitreoretinal Surgery, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0001-9704-3848
Dorota Zarębska-MichalukCollegium Medicum, Jan Kochanowski University of Kielce, 25-369 Kielce, Poland.ORCID 0000-0003-0938-1084
Dominik OdrobinaOphthalmic Clinic, The Voivodeship Hospital, 25-736 Kielce, Poland.
Elżbieta CieślaInstitute of Medical Science, Jan Kochanowski University of Kielce, 25-369 Kielce, Poland.ORCID 0000-0001-6090-9900
Bernadetta Płatkowska-AdamskaCollegium Medicum, Jan Kochanowski University of Kielce, 25-369 Kielce, Poland.ORCID 0000-0003-0289-7168
Michał BiskupOphthalmic Clinic, The Voivodeship Hospital, 25-736 Kielce, Poland.
Paweł PabjanDepartment of Infectious Disease, Provincial Hospital in Kielce, 25-736 Kielce, Poland.
Stanisław GłuszekCollegium Medicum, Jan Kochanowski University of Kielce, 25-369 Kielce, Poland.ORCID 0000-0001-7752-0459
Jerzy MackiewiczDepartment of Vitreoretinal Surgery, Medical University of Lublin, 20-059 Lublin, Poland.
Jan Kochanowski University · PLKielce University of Technology · PLMedical University of Lublin · PL

Funding

Ministry of Science and Higher Education 024/RID/2018/19
6 · The paper itself

Abstract

The purpose of this study was to evaluate the persistent changes in microvascular parameters based on optical coherence tomography angiography (OCTA) in patients hospitalized due to COVID-19 bilateral pneumonia. The case-control prospective study was carried out among 49 patients with COVID-19 and 45 healthy age- and gender-matched 2 and 8 months after hospital discharge. We found a significantly decreased vessel density (VD) in superficial capillary plexus (SCP) in COVID-19 patients. Significantly decreased vessel density (VD) in the superficial capillary plexus (SCP), the deep capillary plexus (DCP), and choriocapillaris (CC), with significantly increased vessel density observed in the choriocapillaris in the foveal area (FCC). The foveal avascular zone in DCP (FAZd) was significantly increased in the COVID-19 group. We found differences between OCTA parameters according to gender. The foveal VD in SCP and DCP was significantly decreased in women compared to men. The FAZ area in SCP (FAZs) and superior VD in the choriocapillaris (SCC) were significantly increased in women. In conclusion, we noticed persistent changes in the ocular parameters of OCTA in COVID-19 patients. At the second follow-up visit, we observed a widened FAZ zone in SCP and decreased VD in some regions of the retina and choroid.

Indexed as

COVID-19optical coherence tomography angiographypersistent microvascular changesSARS-CoV-2vessel density

Identifiers

PMID37048610
PMCPMC10095143
OpenAlexW4361221409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.