ArticleJournal of clinical medicine2023
Safety and Efficacy of Ab Interno XEN 45 Gel Stent in Patients with Glaucoma and High Myopia.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Minimally Invasive Bleb Surgery for Glaucoma: A Health Technology Assessment.Ontario health technology assessment series · 2024Pooled it
- Gonioscopy-assisted transluminal trabeculotomy with phacoemulsification in high myopia versus non-high myopia with open-angle glaucoma-A comparative study.Indian journal of ophthalmology · 2026Article
- Surgical outcomes of trabecular micro-bypass minimally invasive glaucoma surgery devices in eyes with high myopia: a 24-month retrospective multicenter cohort study.Eye and vision (London, England) · 2026Article
- Research priorities for diagnostics, progression monitoring, and treatment of glaucoma in myopic eyes.Eye (London, England) · 2026Article
- Influence of High Myopia on Outcomes of iStent Inject W Implantation Combined with Cataract Surgery up to 24 Months of Follow-Up.Journal of clinical medicine · 2026Article
- Update on XEN Gel Stent: A Narrative Review on Indications, Surgical Technique, and Postoperative Management.Ophthalmology and therapy · 2026Review
- Efficacy and Safety of Open-Conjunctiva Ab Externo 63 µm vs. 45 µm XENJournal of clinical medicine · 2025Article
- Comparison of trabeculectomy and gonioscopy-assisted transluminal trabeculotomy results in long eyes wıth open-angle glaucoma.International ophthalmology · 2025Article
- In Vivo Optical Coherence Tomography Outcomes of Hypotony After Trabeculectomy Management with Autologous Blood Injection: A Single-Center Retrospective Study.Journal of clinical medicine · 2025Article
- XEN45 gel stent in the treatment of pigmentary glaucoma: A two-year follow-up.European journal of ophthalmology · 2025Article
- Complications of XEN gel stent implantation for the treatment of glaucoma: a systematic review.Frontiers in medicine · 2024Review
- Effectiveness and Safety of Xen Gel Stent in Glaucoma Surgery: A Systematic Review of the Literature.Journal of clinical medicine · 2023Review
- Comparative efficacy and safety of ab-interno XEN 45 gel implantation versus trabeculectomy for glaucoma: a systematic review and meta-analysis.Therapeutic advances in ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study reports on the safety and efficacy of Xen 45 in patients with glaucoma and high myopia. It was a retrospective study including patients with high myopia (>6D) who underwent Xen implant with 2 years of follow-up. The primary outcome was to report the incidence of hypotony (IOP ≤ 5 mmHg) and hypotony-related complications. Patients with high myopia treated with mitomycin-C-augmented trabeculectomy were included as a control group. We included 14 consecutive patients who underwent Xen implant (seven eyes) and trabeculectomy (seven eyes). The mean myopia was -14.71 ± 5.36 and -15.07 ± 6.11 in the trabeculectomy and Xen groups, respectively (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.