Evidence map›Paper›PMID 37048555›Full record

ArticleJournal of clinical medicine2023

Topical Application of Peptide Nucleic Acid Antisense Oligonucleotide for MMP-1 and Its Potential Anti-Aging Properties.

Young In Lee, Sang Gyu Lee, Inhee Jung, Jangmi Suk, Chaemin Baeg, Seon-Young Han, Jeong Yeon Seo, Daram Jung, Yeasel Jeon, Ju Hee Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Molecular Targets in Modern Cosmetic Science.Molecules (Basel, Switzerland) · 2026
    Review
  3. Frontiers in aging · 2026
    Article
  4. Antimicrobial and prebiotic properties ofIranian journal of microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Young In LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-6831-7379
Sang Gyu LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-6237-9031
Inhee JungGlobal Medical Research Center, Seoul 06526, Republic of Korea.
Jangmi SukGlobal Medical Research Center, Seoul 06526, Republic of Korea.
Chaemin BaegGlobal Medical Research Center, Seoul 06526, Republic of Korea.
Seon-Young HanOliPass Corporation, Yongin-si 17015, Republic of Korea.
Jeong Yeon SeoOliPass Corporation, Yongin-si 17015, Republic of Korea.
Daram JungOliPass Corporation, Yongin-si 17015, Republic of Korea.
Yeasel JeonOliPass Corporation, Yongin-si 17015, Republic of Korea.
Ju Hee LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Seoul Medical Center · KRYonsei University · KR

Funding

OLIPASS Corporation xxx-xxx
6 · The paper itself

Abstract

Matrix metalloproteinase-1 (MMP-1) is a zinc-containing endopeptidase that degrades dermal collagen and other extracellular matrix molecules. It is recognized as one of the most important indicators of cellular senescence and age-related skin changes. Here, we introduced a novel MMP-1 peptide nucleic acid (PNA) derivative-

Indexed as

anti-agingcollagen Imatrix metalloproteinase-1peptide nucleic acidPNA-20 CEF

Identifiers

PMID37048555
PMCPMC10095221
OpenAlexW4360857187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.