Evidence map›Paper›PMID 37048344›Full record

ArticleFoods (Basel, Switzerland)2023

Formation and Characterization of Self-Assembled Rice Protein Hydrolysate Nanoparticles as Soy Isoflavone Delivery Systems.

Haoran Mo, Xiuwen Chen, Bo Cui, Yangling Chen, Maolong Chen, Zhou Xu, Li Wen, Yunhui Cheng, Ye Jiao

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haoran MoSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.
Xiuwen ChenSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.
Bo CuiSchool of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China.
Yangling ChenSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.
Maolong ChenSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.ORCID 0000-0002-3818-4955
Zhou XuSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.ORCID 0000-0002-6128-142X
Li WenSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.ORCID 0000-0002-8671-2046
Yunhui ChengSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.
Ye JiaoSchool of Food Science and Bioengineering, Changsha University of Science & Technology, Changsha 410114, China.

Funding

National Natural Science Foundation of China 32102114Natural Science Foundation of Hunan Province 2021JJ40566Natural Science Foundation of Hunan Province 2022JJ30587Taishan Industry Leading Talents LJNY202004Taishan Industry Leading Talents TSCY20190103
6 · The paper itself

Abstract

In this study, soy isoflavones-loaded nanoparticles were prepared using rice proteins (RPs) hydrolyzed by four types of enzyme (alcalase, neutrase, trypsin, and flavorzyme). After optimizing the preparation conditions, the encapsulation efficiency (EE) of the nanoparticles ranged from 61.16% ± 0.92% to 90.65% ± 0.19%. The RPs that were hydrolyzed by flavorzyme with a molecular weight of <5 KDa showed better characters on the formation of nanoparticles, and the formed nanoparticles had the highest EE and loading capacity (9.06%), the smallest particle size (64.77 nm), the lowest polymer dispersity index (0.19), and the lowest zeta potential (-25.64 mV).The results of Fourier transform ion cyclotron resonance, X-ray diffraction, and fluorescence spectroscopy showed that the nanoparticles were successfully encapsulated. The study of interaction showed that the formation of nanoparticles may depend mainly on hydrogen bonds, but other interactions, such as hydrophobic interactions and electrostatic interactions, cannot be ignored. After encapsulation, the pH stability, temperature stability, ionic stability, and oxidation resistance of the nanoparticles were enhanced. Moreover, the in vitro release experiment showed that the encapsulated nanoparticles had a certain protective effect on soybean isoflavones. In summary, rice protein hydrolysates are promising carriers for soybean isoflavones.

Indexed as

nanoparticles transport systemsrice proteinsoy isoflavone

Identifiers

PMID37048344
PMCPMC10094372

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.