Evidence map›Paper›PMID 37048092›Full record

ArticleCells2023

Adipose Tissue Caveolin-1 Upregulation in Obesity Involves TNF-α/NF-κB Mediated Signaling.

Ashraf Al Madhoun, Shihab Kochumon, Dania Haddad, Reeby Thomas, Rasheeba Nizam, Lavina Miranda, Sardar Sindhu, Milad S Bitar, Rasheed Ahmad, Fahd Al-Mulla

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Caveolae: Metabolic Platforms at the Crossroads of Health and Disease.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ashraf Al MadhounGenetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.ORCID 0000-0001-8593-3878
Shihab KochumonImmunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Dania HaddadGenetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.ORCID 0000-0001-6687-6361
Reeby ThomasImmunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.ORCID 0000-0001-9933-0285
Rasheeba NizamGenetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.ORCID 0000-0002-4762-9469
Lavina MirandaAnimal and Imaging Core Facilities, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Sardar SindhuAnimal and Imaging Core Facilities, Dasman Diabetes Institute, Dasman 15462, Kuwait.ORCID 0000-0001-9936-1575
Milad S BitarGenetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Rasheed AhmadImmunology & Microbiology Department, Dasman Diabetes Institute, Dasman 15462, Kuwait.ORCID 0000-0001-5746-0743
Fahd Al-MullaGenetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.ORCID 0000-0001-5409-3829
Dasman Diabetes Institute · KWKuwait University · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is characterized by chronic low-grade inflammation. Obese people have higher levels of caveolin-1 (CAV1), a structural and functional protein present in adipose tissues (ATs). We aimed to define the inflammatory mediators that influence

Indexed as

Caveolin 1NF-kappa BObesityTumor Necrosis Factor-alphaAdipose TissueAnimalsHumansInflammationMiceSignal TransductionUp-RegulationCAV1 protein, humanCav1 protein, mouseCaveolin 1NF-kappa BTumor Necrosis Factor-alphaadipose tissuecaveolin-1cytokinesmetabolic inflammationNF-κBobesityTNF-α

Identifiers

PMID37048092
PMCPMC10093236
OpenAlexW4361008238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.