Evidence map›Paper›PMID 37047754›Full record

ArticleInternational journal of molecular sciences2023

Atorvastatin Can Modulate DNA Damage Repair in Endothelial Cells Exposed to Mitomycin C.

Maxim Sinitsky, Maxim Asanov, Anna Sinitskaya, Daria Shishkova, Maria Khutornaya, Varvara Minina, Anastasia Ponasenko

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maxim SinitskyLaboratory of Genome Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo 650002, Russia.ORCID 0000-0002-4824-2418
Maxim AsanovLaboratory of Genome Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo 650002, Russia.
Anna SinitskayaLaboratory of Genome Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo 650002, Russia.ORCID 0000-0002-4467-8732
Daria ShishkovaLaboratory for Molecular, Translation and Digital Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo 650002, Russia.ORCID 0000-0002-1518-3888
Maria KhutornayaLaboratory of Genome Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo 650002, Russia.
Varvara MininaDepartment of Genetic and Fundamental Medicine, Kemerovo State University, Kemerovo 650000, Russia.ORCID 0000-0003-3485-9123
Anastasia PonasenkoLaboratory of Genome Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo 650002, Russia.ORCID 0000-0002-3002-2863
Kemerovo State University · RU

Funding

Russian Science Foundation 21-75-10052
6 · The paper itself

Abstract

HMG-CoA reductase inhibitors (statins) are widely used in the therapy of atherosclerosis and have a number of pleiotropic effects, including DNA repair regulation. We studied the cytogenetic damage and the expression of DNA repair genes (

Indexed as

AtherosclerosisHydroxymethylglutaryl-CoA Reductase InhibitorsAtorvastatinDNA DamageDNA RepairEndothelial CellsHumansMitomycinAtorvastatinHydroxymethylglutaryl-CoA Reductase InhibitorsMitomycinatorvastatincytogeneticsDNA damagegene expressiongenotoxic stressmicronucleus assay

Identifiers

PMID37047754
PMCPMC10094919
OpenAlexW4362610182

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.