Evidence map›Paper›PMID 37047732›Full record

ArticleInternational journal of molecular sciences2023

Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells.

Cecilia Astigiano, Francesco Piacente, Maria Elena Laugieri, Andrea Benzi, Christian A Di Buduo, Carolina P Miguel, Debora Soncini, Michele Cea, Antonella Antonelli, Mauro Magnani and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Pannexins in the vasculature.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Cecilia AstigianoDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV, 1, 16132 Genova, Italy.
Francesco PiacenteDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV, 1, 16132 Genova, Italy.ORCID 0000-0001-5470-5987
Maria Elena LaugieriDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV, 1, 16132 Genova, Italy.
Andrea BenziDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV, 1, 16132 Genova, Italy.
Christian A Di BuduoDepartment of Molecular Medicine, University of Pavia, Via C. Forlanini 6, 27100 Pavia, Italy.ORCID 0000-0002-6472-2008
Carolina P MiguelDepartment of Molecular Medicine, University of Pavia, Via C. Forlanini 6, 27100 Pavia, Italy.ORCID 0000-0001-6708-8869
Debora SonciniDepartment of Internal Medicine, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy.ORCID 0000-0001-5156-498X
Michele CeaDepartment of Internal Medicine, University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy.ORCID 0000-0002-1530-6729
Antonella AntonelliDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, Via Saffi 2, 61029 Urbino, Italy.ORCID 0000-0002-5931-4616
Mauro MagnaniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, Via Saffi 2, 61029 Urbino, Italy.ORCID 0000-0001-6456-6626
Alessandra BalduiniDepartment of Molecular Medicine, University of Pavia, Via C. Forlanini 6, 27100 Pavia, Italy.
Antonio De FloraDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV, 1, 16132 Genova, Italy.
Santina BruzzoneDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV, 1, 16132 Genova, Italy.ORCID 0000-0003-2034-3716
University of Genoa · ITOspedale Policlinico San Martino · ITUniversity of Pavia · ITUniversity of Urbino · ITTufts University · US

Funding

Fondazione Compagnia di San Paolo Bando TrapezioItalian Ministry of University and Research PRIN2017Z5LR5Z_003University of Genova FRA
6 · The paper itself

Abstract

Sirtuin 6 (SIRT6) is a member of the mammalian NAD

Indexed as

Human Umbilical Vein Endothelial CellsSirtuinsAdenosine TriphosphateHumansNADTumor Necrosis Factor-alphaAdenosine TriphosphateNADSIRT6 protein, humanSirtuinsTumor Necrosis Factor-alphaATPendotheliuminflammationNAD+purinergic receptorsSIRT6

Identifiers

PMID37047732
PMCPMC10095398
OpenAlexW4362620127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.