Evidence map›Paper›PMID 37047690›Full record

ArticleInternational journal of molecular sciences2023

1,25(OH)

Isabella Sanseverino, Arturo Ottavio Rinaldi, Cristina Purificato, Antonio Cortese, Enrico Millefiorini, Maria Cristina Gauzzi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Isabella SanseverinoNational Center for Global Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Arturo Ottavio RinaldiNational Center for Global Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Cristina PurificatoNational Center for Global Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Antonio CorteseMultiple Sclerosis Center, Sapienza University of Rome, 00161 Rome, Italy.
Enrico MillefioriniMultiple Sclerosis Center, Sapienza University of Rome, 00161 Rome, Italy.
Maria Cristina GauzziNational Center for Global Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Istituto Superiore di Sanità · ITSapienza University of Rome · IT

Funding

FISM - Italian Foundation Multiple Sclerosis 2009/R/12
6 · The paper itself

Abstract

Immune mechanisms play an essential role in driving multiple sclerosis (MS) and altered trafficking and/or activation of dendritic cells (DC) were observed in the central nervous system and cerebrospinal fluid of MS patients. Interferon β (IFNβ) has been used as a first-line therapy in MS for almost three decades and vitamin D deficiency is a recognized environmental risk factor for MS. Both IFNβ and vitamin D modulate DC functions. Here, we studied the response to 1,25-dihydoxyvitamin D3 (1,25(OH)

Indexed as

Multiple SclerosisVitamin DChemokinesCytokinesHumansVitaminsChemokinesCytokinesVitamin DVitaminschemokinecytokineimmune pathophysiologymodifiable environmental factormonocyte-derived dendritic cellmultiple sclerosistype I IFNvitamin D

Identifiers

PMID37047690
PMCPMC10094841
OpenAlexW4362558572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.