Evidence map›Paper›PMID 37047689›Full record

ArticleInternational journal of molecular sciences2023

Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice.

Anuradha Dhingra, John W Tobias, Nancy J Philp, Kathleen Boesze-Battaglia

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anuradha DhingraDepartment of Basic and Translational Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
John W TobiasPenn Genomics and Sequencing Core, Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Nancy J PhilpDepartment of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID 0000-0001-7028-0448
Kathleen Boesze-BattagliaDepartment of Basic and Translational Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-0962-0508
University of Pennsylvania · USThomas Jefferson University · US

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI CLAIRE H MITCHELL · 1985 to 2026
$19.5M
MEMBRANE FUSION IN RETINAL ROD OUTER SEGMENTSR01EY010420 · NEI · UNIV OF MED/DENT NJ-SCH OSTEOPATHIC MED · PI BOESZE-BATTAGLIA, KATHLEEN · 1999 to 2016
$4.7M
Recycling of Metabolites from Ingested Outer Segments Supports Visual FunctionR01EY026525 · NEI · UNIVERSITY OF PENNSYLVANIA · PI BOESZE-BATTAGLIA, KATHLEEN, PHILP, NANCY JEAN · 2016 to 2023
$3.4M
Microsomal Transfer Protein Modulates Lipoprotein Metabolism and Retinal lipid HomeostasisR21EY032743 · NEI · UNIVERSITY OF PENNSYLVANIA · PI BOESZE-BATTAGLIA, KATHLEEN, HUSSAIN, M MAHMOOD · 2022 to 2023
$454k
NEI NIH HHS P30 EY001583NEI NIH HHS R01 EY010420NEI NIH HHS R01 EY026525NEI NIH HHS R21 EY032743
6 · The paper itself

Abstract

LC3b (

Indexed as

Microtubule-Associated ProteinsTranscriptomeAnimalsAutophagyInflammationLipidsMaleMicePhagocytosisRetinal Pigment EpitheliumLipidsMap1lc3b protein, mouseMicrotubule-Associated Proteinscholesterol metabolismcholesterol traffickingfatty acid metabolisminflammationLC3-associated phagocytosis (LAP)monocarboxylate transportersperoxisomesretinal pigment epithelium (RPE)transcriptomics

Identifiers

PMID37047689
PMCPMC10095460
OpenAlexW4362559291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.