Evidence map›Paper›PMID 37047578›Full record

ArticleInternational journal of molecular sciences2023

The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against

Justyna Roszkowiak, Siobhán McClean, Aleksandra M Mirończuk, Daria Augustyniak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Justyna RoszkowiakDepartment of Pathogen Biology and Immunology, Faculty of Biological Sciences, University of Wroclaw, 51-148 Wroclaw, Poland.ORCID 0000-0001-7993-0152
Siobhán McCleanSchool of Biomolecular and Biomedical Sciences and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, D04 V1W8 Dublin, Ireland.ORCID 0000-0001-6389-2542
Aleksandra M MirończukLaboratory for Biosustainability, Institute of Environmental Biology, Wroclaw University of Environmental and Life Sciences, 51-631 Wroclaw, Poland.ORCID 0000-0003-1604-1635
Daria AugustyniakDepartment of Pathogen Biology and Immunology, Faculty of Biological Sciences, University of Wroclaw, 51-148 Wroclaw, Poland.ORCID 0000-0002-0547-3937
University of Wrocław · PLUniversity College Dublin · IEWrocław University of Environmental and Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil elastase (NE) contributes to innate antibacterial defense at both the intracellular (phagocytosis) and extracellular (degranulation, NETosis) levels.

Indexed as

Leukocyte ElastaseMoraxella catarrhalisBacteriaBacterial Outer Membrane ProteinsChromatography, LiquidHumansTandem Mass SpectrometryBacterial Outer Membrane ProteinsLeukocyte Elastaseanti-virulence actionbactericidal actioncomplementCOPDinflammationMoraxella catarrhalisneutrophil elastaseOMP CDouter membrane proteins (OMPs)outer membrane vesicles (OMVs)TEM

Identifiers

PMID37047578
PMCPMC10094786
OpenAlexW4362589617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.