Evidence map›Paper›PMID 37047542›Full record

ArticleInternational journal of molecular sciences2023

A Novel E3 Probiotics Formula Restored Gut Dysbiosis and Remodelled Gut Microbial Network and Microbiome Dysbiosis Index (MDI) in Southern Chinese Adult Psoriasis Patients.

Chi Tung Choy, Un Kei Chan, Pui Ling Kella Siu, Junwei Zhou, Chi Ho Wong, Yuk Wai Lee, Ho Wang Chan, Joseph Chi Ching Tsui, Steven King Fan Loo, Stephen Kwok Wing Tsui

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Article
  8. Immunomodulatory Effects ofCurrent issues in molecular biology · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Gut microbiota and psoriasis: pathogenesis, targeted therapy, and future directions.Frontiers in cellular and infection microbiology · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chi Tung ChoyMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Un Kei ChanMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Pui Ling Kella SiuMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Junwei ZhouMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Chi Ho WongMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Yuk Wai LeeMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Ho Wang ChanMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Joseph Chi Ching TsuiMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Steven King Fan LooMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.
Stephen Kwok Wing TsuiMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong, China.ORCID 0000-0003-0686-4259
Chinese University of Hong Kong · HK

Funding

Hong Kong Society of Gut Microbiome Nil
6 · The paper itself

Abstract

Psoriasis is a common chronic immune-mediated inflammatory skin disease with the association of various comorbidities. Despite the introduction of highly effective biologic therapies over the past few decades, the exact trigger for an immune reaction in psoriasis is unclear. With the majority of immune cells residing in the gut, the effect of gut microbiome dysbiosis goes beyond the gastrointestinal site and may exacerbate inflammation and regulate the immune system elsewhere, including but not limited to the skin via the gut-skin axis. In order to delineate the role of the gut microbiome in Southern Chinese psoriasis patients, we performed targeted 16S rRNA sequencing and comprehensive bioinformatic analysis to compare the gut microbiome profile of 58 psoriasis patients against 49 healthy local subjects presumably with similar lifestyles.

Indexed as

DysbiosisGastrointestinal MicrobiomeProbioticsPsoriasisAdultEast Asian PeopleHumansRNA, Ribosomal, 16SRNA, Ribosomal, 16Sgut dysbiosis indexgut microbiomemetagenomicsParabacteroides distasonisprobioticspsoriasis

Identifiers

PMID37047542
PMCPMC10094986
OpenAlexW4362583592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.