Observational studyInternational journal of molecular sciences2023
Reduced High-Density Lipoprotein Cholesterol Is an Independent Determinant of Altered Bone Quality in Women with Type 2 Diabetes.
Observational study in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Association between uric acid to high-density lipoprotein cholesterol ratio (UHR) and osteoporosis in type 2 diabetes with MASLD.Asia Pacific journal of clinical nutrition · 2026Article
- Clinical Manifestations and Risk Factors of Osteoporosis in Patients with Type 2 Diabetes Mellitus.Journal of inflammation research · 2026Article
- Association between the serum uric acid to HDL cholesterol ratio and forearm bone mineral density in middle-aged and older adults.Frontiers in endocrinology · 2026Article
- Bone microstructure and TBS in diabetes: what have we learned? A narrative review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Review
- Multifaceted environmental factors linked to metabolic dysfunction-associated fatty liver disease: an environment-wide association study.BMC public health · 2025Article
- Nonlinear relationship between lumbar bone mineral density and high-density lipoprotein cholesterol in patients with type 2 diabetes.Frontiers in endocrinology · 2025Article
- Assessment of fracture risk in diabetic patients.Journal of diabetes and metabolic disorders · 2024Review
- Remnant cholesterol is associated with hip BMD and low bone mass in young and middle-aged men: a cross-sectional study.Journal of endocrinological investigation · 2024Article
- The association between variability of risk factors and complications in type 2 diabetes mellitus: a retrospective study.Scientific reports · 2024Article
- Waist circumference, among metabolic syndrome components, predicts degraded trabecular bone score: a retrospective study of a female population from the 2005-2008 NHANES cohorts.Frontiers in endocrinology · 2024Article
- Non-diabetic elderly populations: the MHR as a protective factor against bone abnormalities.Frontiers in endocrinology · 2024Article
- Trabecular Bone Score (TBS) in Individuals with Type 2 Diabetes Mellitus: An Updated Review.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
Type 2 diabetes mellitus (T2DM) is associated with an increased fracture risk. Our study aimed to explore differences in bone alterations between T2DM women and controls and to assess clinical predictors of bone impairment in T2DM. For this observational case control study, we recruited 126 T2DM female patients and 117 non-diabetic, age- and BMI-comparable women, who underwent clinical examination, routine biochemistry and dual-energy X-ray absorptiometry (DXA) scans for bone mineral density (BMD) and trabecular bone score (TBS) assessment-derived indexes. These were correlated to metabolic parameters, such as glycemic control and lipid profile, by bivariate analyses, and significant variables were entered in multivariate adjusted models to detect independent determinants of altered bone status in diabetes. The T2DM patients were less represented in the normal bone category compared with controls (5% vs. 12%;
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