Trial reportInternational journal of molecular sciences2023
Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation.
Trial report in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Repairing alveolar bone defect using demineralized dentin grafts: a meta-analysis of randomized controlled trials.BMC oral health · 2024Pooled it
- The key role of RANKL and OPG as molecular biomarkers in bone remodeling associated with different grafts regarding socket preservation: A systematic review.Journal of Taibah University Medical Sciences · 2026Review
- Bone Substitutes in Alveolar Ridge Augmentation: A Narrative Literature Review.Journal of functional biomaterials · 2026Review
- Autogenous dentin grafts in implant dentistry: A scoping review of clinical applications and processing protocols.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Comparative effectiveness of autologous particulate dentin graft for alveolar ridge preservation: a network meta-analysis of randomized controlled trials.BMC oral health · 2025Article
- Radiographic and histomorphometric evaluation of Autogenous Particulated Dentin for Alveolar Ridge Preservation: A Systematic Review and Meta-analyses.Journal of clinical and experimental dentistry · 2025Review
- Autologous Tooth-Derived Biomaterials in Alveolar Bone Regeneration: A Systematic Review of Clinical Outcomes and Histological Evidence.Journal of functional biomaterials · 2025Review
- Eighty-Four-Month Clinical Outcomes of Autologous Dentin Graft Using Tooth TransformerJournal of functional biomaterials · 2025Article
- The Microbial Diversity and Biofilm Characteristics of d-PTFE Membranes Used for Socket Preservation: A Randomized Controlled Clinical Trial.Journal of functional biomaterials · 2025Article
- Review
- Polydeoxyribonucleotides Pre-Clinical Findings in Bone Healing: A Scoping Review.Dentistry journal · 2023Article
- Biomaterials for Alveolar Ridge Preservation as a Preoperative Procedure for Implant Treatment: History and Current Evidence.Bioengineering (Basel, Switzerland) · 2023Review
- Incorporating Moldable Demineralized Dentin Matrix into Treatment for a Jaw Cyst.Journal of functional biomaterials · 2023Article
- Dentin-derived alveolar bone graft for alveolar augmentation: A systematic review.Journal of oral biology and craniofacial researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
This prospective, randomized, controlled clinical trial reports clinical, radiographic, histologic and immunohistochemical results of autologous dentin graft (ADG) and its comparison with a mixture of bovine xenograft with autologous bone (BX+AB). After tooth extraction in the esthetic zone of maxilla, the alveolar ridge of 20 patients in the test group was augmented with ADG, while 17 patients in the control group received the combination of BX+AB. Cone beam computed tomography (CBCT) was performed before tooth extraction and after 4 months when a total of 22 bone biopsies were harvested and subjected to histological and immunohistochemical analysis. Radiological analysis showed comparable results of bone dimension loss in both groups. Quantitative histologic analysis showed comparable results with no statistically significant differences between the groups. Immunohistochemical staining with TNF-α and BMP-4 antibodies revealed immunopositivity in both groups. A statistically significant difference between the groups was found in the intensity of TNF-α in the area of newly formed bone (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.