Evidence map›Paper›PMID 37047366›Full record

ArticleInternational journal of molecular sciences2023

Antiproliferative Mechanisms of a Polyphenolic Combination of Kaempferol and Fisetin in Triple-Negative Breast Cancer Cells.

Mohd Afzal, Abdullah Alarifi, Abdalnaser Mahmoud Karami, Rashid Ayub, Naaser A Y Abduh, Waseem Sharaf Saeed, Mohd Muddassir

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Exploring the Functional Properties of Leaves ofAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohd AfzalDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-5668-6038
Abdullah AlarifiDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Abdalnaser Mahmoud KaramiDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Rashid AyubDepartment of Science Technology Unit, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-5239-2443
Naaser A Y AbduhDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Waseem Sharaf SaeedRestorative Dental Sciences Department, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.ORCID 0000-0002-5254-5665
Mohd MuddassirDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-7069-2557

Funding

King Saud University IFKSURG-2-1260
6 · The paper itself

Abstract

Herein, we investigate the combinatorial therapeutic effects of naturally occurring flavonoids kaempferol (K) and fisetin (F) on triple-negative breast cancer (TNBC: MDA-MB-231 cell line). Dose-dependent MTT assay results show that K and F exhibited cytotoxicity in MDA-MB-231 cells at 62 and 75 μM (IC

Indexed as

KaempferolsTriple Negative Breast NeoplasmsApoptosisCell Line, TumorCell ProliferationFlavonolsHumansfisetinFlavonolsKaempferolsantioxidantbreast cancerfisetinflavonoidskaempferol

Identifiers

PMID37047366
PMCPMC10094218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.