Evidence map›Paper›PMID 37047363›Full record

ReviewInternational journal of molecular sciences2023

The Role of Adipokines in the Pathogenesis of Psoriasis.

Kajetan Kiełbowski, Estera Bakinowska, Piotr Ostrowski, Bartłomiej Pala, Ewa Gromowska, Klaudia Gurazda, Paweł Dec, Andrzej Modrzejewski, Andrzej Pawlik

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kajetan KiełbowskiDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-8227-6753
Estera BakinowskaDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Piotr OstrowskiDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-9136-8406
Bartłomiej PalaDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Ewa GromowskaDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Klaudia GurazdaDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Paweł DecPlastic and Reconstructive Surgery Department, 109 Military Hospital, 71-422 Szczecin, Poland.ORCID 0000-0002-8514-3259
Andrzej ModrzejewskiDepartment of Surgery, Pomeranian Medical University, 71-422 Szczecin, Poland.
Andrzej PawlikDepartment of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-6557-1208
Pomeranian Medical University · PL1 Military Clinical Hospital with Outpatient Clinic · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic and immune-mediated skin condition characterized by pro-inflammatory cytokines and keratinocyte hyperproliferation. Dendritic cells, T lymphocytes, and keratinocytes represent the main cell subtypes involved in the pathogenesis of psoriasis, while the interleukin-23 (IL-23)/IL-17 pathway enhances the disease progression. Human adipose tissue is an endocrine organ, which secretes multiple proteins, known as adipokines, such as adiponectin, leptin, visfatin, or resistin. Current evidence highlights the immunomodulatory roles of adipokines, which may contribute to the progression or suppression of psoriasis. A better understanding of the complexity of psoriasis pathophysiology linked with adipokines could result in developing novel diagnostic or therapeutic strategies. This review aims to present the pathogenesis of psoriasis and the roles of adipokines in this process.

Indexed as

AdipokinesPsoriasisAdiponectinAdipose TissueHumansLeptinResistinAdipokinesAdiponectinLeptinResistinadipokinesadiponectincytokinesinflammationleptinpsoriasis

Identifiers

PMID37047363
PMCPMC10094354
OpenAlexW4361283984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.