ArticleInternational journal of molecular sciences2023
Synthesis and Structure-Activity Relationship of Salvinal Derivatives as Potent Microtubule Inhibitors.
Chi-I Chang, Cheng-Chih Hsieh, Yung-Shung Wein, Ching-Chuan Kuo, Chi-Yen Chang, Jrhau Lung, Jong-Yuh Cherng, Po-Chen Chu, Jang-Yang Chang, Yueh-Hsiung Kuo
Open access · goldAbstract read
In one paragraphArticle in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors at 7 institutions in 1 country.
Chi-I ChangDepartment of Biological Science and Technology, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Cheng-Chih HsiehDepartment of Pharmacy, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Yung-Shung WeinDepartment of Chemistry, National Taiwan University, Taipei 114, Taiwan.
Ching-Chuan KuoInstitute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli 350, Taiwan.
Chi-Yen ChangNational Institute of Cancer Research, National Health Research Institutes, Miaoli 350, Taiwan.
Jrhau LungDepartment of Medical Research and Development, Chiayi Chang Gung Memorial Hospital, Chiayi Branch, Chiayi 613, Taiwan.ORCID 0000-0003-2100-3713 Jong-Yuh CherngDepartment of Chemistry and Biochemistry, National Chung Cheng University, Chiayi 613, Taiwan.
Po-Chen ChuDepartment of Cosmeceutics and Graduate Institute of Cosmeceutic, China Medical University, Taichung 404, Taiwan.
Jang-Yang ChangInstitute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli 350, Taiwan.
Yueh-Hsiung KuoDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Pharmacy, China Medical University, Taichung 404, Taiwan.ORCID 0000-0001-5935-6755 National Health Research Institutes · TWAsia University · TWChiayi Chang Gung Memorial Hospital · TWChina Medical University · TWKaohsiung Veterans General Hospital · TWNational Chung Cheng University · TWNational Taiwan University · TW
Funding
Department of Health Clinical Trial and Research Center of Excellent DOH102-TD-C-111-004National Health Research Institutes CA-099-PP-08National Science Council NSC98-2320-B-400-003-MY3;, NSC99-2323-B-400-006Tri-Service General Hospital TSGH-C99-111, TSGH-C100-038
6 · The paper itselfAbstract
Salvinal is a natural lignan isolated from the roots of
Indexed as
Antineoplastic AgentsAldehydesBenzofuransCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMicrotubulesMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipTubulin Modulators5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzo(b)furancarbaldehydeAldehydesAntineoplastic AgentsBenzofuransTubulin Modulatorsanticancerlignanmicrotubule depolymerizationSalvia mitorrhizasalvinal
Identifiers
PMID37047358
PMCPMC10093915
OpenAlexW4361306080
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