Evidence map›Paper›PMID 37047355›Full record

ArticleInternational journal of molecular sciences2023

E-Cigarette Aerosol Condensate Leads to Impaired Coronary Endothelial Cell Health and Restricted Angiogenesis.

Michael Chhor, Esra Tulpar, Tara Nguyen, Charles G Cranfield, Catherine A Gorrie, Yik Lung Chan, Hui Chen, Brian G Oliver, Lana McClements, Kristine C McGrath

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Michael ChhorSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Esra TulparSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Tara NguyenSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Charles G CranfieldSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0003-3608-5440
Catherine A GorrieSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Yik Lung ChanSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Hui ChenSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0001-6883-3752
Brian G OliverSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-7122-9262
Lana McClementsSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Kristine C McGrathSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-6244-3929
University of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) is a leading cause of mortality worldwide, with cigarette smoking being a major preventable risk factor. Smoking cessation can be difficult due to the addictive nature of nicotine and the withdrawal symptoms following cessation. Electronic cigarettes (e-Cigs) have emerged as an alternative smoking cessation device, which has been increasingly used by non-smokers; however, the cardiovascular effects surrounding the use of e-Cigs remains unclear. This study aimed to investigate the effects of e-Cig aerosol condensate (EAC) (0 mg and 18 mg nicotine) in vitro on human coronary artery endothelial cells (HCAEC) and in vivo on the cardiovascular system using a mouse model of 'e-vaping'. In vitro results show a decrease in cell viability of HCAEC when exposed to EAC either directly or after exposure to conditioned lung cell media (

Indexed as

Cardiovascular DiseasesElectronic Nicotine Delivery SystemsAerosolsAnimalsEndothelial CellsHumansIntercellular Adhesion Molecule-1MiceNicotineTacrolimus Binding ProteinsAerosolsFKBPL protein, humanIntercellular Adhesion Molecule-1NicotineTacrolimus Binding Proteinsatherosclerosiscardiovascular diseasee-vapingnicotinesmoking

Identifiers

PMID37047355
PMCPMC10094580
OpenAlexW4361284418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.