Evidence map›Paper›PMID 37047328›Full record

ReviewInternational journal of molecular sciences2023

3D Bioprinting for Next-Generation Personalized Medicine.

Ethan Hau Yin Lam, Fengqing Yu, Sabrina Zhu, Zongjie Wang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

  1. Critical Systematic Review of 3D Bioprinting in Biomedicine.International journal of molecular sciences · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. 3D Bioprinting Strategies in Autoimmune Disease Models.International journal of molecular sciences · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. The nerve center of organ engineering.Nature communications · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ethan Hau Yin LamFaculty of Arts and Science, University of Toronto, Toronto, ON M5S 3G3, Canada.ORCID 0009-0007-7835-3016
Fengqing YuFaculty of Arts and Science, University of Toronto, Toronto, ON M5S 3G3, Canada.
Sabrina ZhuFaculty of Arts and Science, University of Toronto, Toronto, ON M5S 3G3, Canada.
Zongjie WangLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.ORCID 0000-0001-9900-7197
University of Toronto · CANorthwestern University · US

Funding

STEM Fellowship Indicium research competition
6 · The paper itself

Abstract

In the past decade, immense progress has been made in advancing personalized medicine to effectively address patient-specific disease complexities in order to develop individualized treatment strategies. In particular, the emergence of 3D bioprinting for in vitro models of tissue and organ engineering presents novel opportunities to improve personalized medicine. However, the existing bioprinted constructs are not yet able to fulfill the ultimate goal: an anatomically realistic organ with mature biological functions. Current bioprinting approaches have technical challenges in terms of precise cell deposition, effective differentiation, proper vascularization, and innervation. This review introduces the principles and realizations of bioprinting with a strong focus on the predominant techniques, including extrusion printing and digital light processing (DLP). We further discussed the applications of bioprinted constructs, including the engraftment of stem cells as personalized implants for regenerative medicine and in vitro high-throughput drug development models for drug discovery. While no one-size-fits-all approach to bioprinting has emerged, the rapid progress and promising results of preliminary studies have demonstrated that bioprinting could serve as an empowering technology to resolve critical challenges in personalized medicine.

Indexed as

BioprintingTissue EngineeringHumansPrecision MedicinePrinting, Three-DimensionalRegenerative MedicineTissue Scaffoldsbiomaterialbioprintingdrug discoverypersonalized medicineprecision medicineregenerative medicinestem cell

Identifiers

PMID37047328
PMCPMC10094501
OpenAlexW4361221396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.