Evidence map›Paper›PMID 37047326›Full record

ArticleInternational journal of molecular sciences2023

Oxidative Stress and Endoplasmic Reticulum Stress Contributes to Arecoline and Its Secondary Metabolites-Induced Dyskinesia in Zebrafish Embryos.

Wenhua Yan, Tian Zhang, Shuaiting Li, Yunpeng Wang, Li Zhu, Yu Cao, Xiaofang Lai, Huizhe Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Wenhua YanThe Second Affiliated Hospital of Chongqing Medical University, No.76 Linjiang Road, Yuzhong District, Chongqing 400010, China.
Tian ZhangKey Laboratory of Bio-Rheological Science and Technology, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, No.174 Shazhengjie, Shapingba, Chongqing 400044, China.
Shuaiting LiThe Second Affiliated Hospital of Chongqing Medical University, No.76 Linjiang Road, Yuzhong District, Chongqing 400010, China.
Yunpeng WangThe Second Affiliated Hospital of Chongqing Medical University, No.76 Linjiang Road, Yuzhong District, Chongqing 400010, China.
Li ZhuKey Laboratory of Bio-Rheological Science and Technology, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, No.174 Shazhengjie, Shapingba, Chongqing 400044, China.
Yu CaoKey Laboratory of Bio-Rheological Science and Technology, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, No.174 Shazhengjie, Shapingba, Chongqing 400044, China.
Xiaofang LaiKey Laboratory of Marine Biological Resources and Environment of Jiangsu Province, College of Marine Science and Fisheries, Jiangsu Ocean University, Lianyungang 222005, China.
Huizhe HuangThe Second Affiliated Hospital of Chongqing Medical University, No.76 Linjiang Road, Yuzhong District, Chongqing 400010, China.
Chongqing University · CNChongqing Medical University · CNDalian Medical University · CNSecond Affiliated Hospital of Chongqing Medical University · CN

Funding

China Postdoctoral Science Foundation 2022MD713708National Natural Science Foundation of China 31771619Natural Science Foundation of Chongqing, China cstc2021jcyj-bsh-X0069
6 · The paper itself

Abstract

Areca nut has been listed as one of the most addictive substances, along with tobacco, alcohol and caffeine. Areca nut contains seven psychoactive alkaloids; however, the effects of these alkaloids on embryonic development and motor behavior are rarely addressed in zebrafish embryo-larvae. Herein, we investigated the effects of exposure to three alkaloids (arecoline and secondary metabolites-arecaidine and arecoline

Indexed as

AlkaloidsArecolineAnimalsArecaEndoplasmic Reticulum StressOxidative StressZebrafishAlkaloidsArecolinearecaidinearecolinearecoline N-oxidedyskinesiaendoplasmic reticulum stressoxidative stress

Identifiers

PMID37047326
PMCPMC10094114
OpenAlexW4361213137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.