Evidence map›Paper›PMID 37047318›Full record

ArticleInternational journal of molecular sciences2023

Clinical and Functional Characteristics of the E92K

Elena Kondratyeva, Yuliya Melyanovskaya, Nataliya Bulatenko, Ksenia Davydenko, Alexandra Filatova, Anna Efremova, Mikhail Skoblov, Tatiana Bukharova, Viktoriya Sherman, Anna Voronkova and 15 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 2 institutions in 2 countries.

Elena KondratyevaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0001-6395-0407
Yuliya MelyanovskayaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0002-8814-5532
Nataliya BulatenkoResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Ksenia DavydenkoResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0001-7620-9175
Alexandra FilatovaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Anna EfremovaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Mikhail SkoblovResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0002-7293-3438
Tatiana BukharovaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0003-0481-256X
Viktoriya ShermanResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0003-2206-1528
Anna VoronkovaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0002-8183-7990
Elena ZhekaiteResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Stanislav KrasovskiyResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Elena AmelinaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Nika PetrovaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Alexander PolyakovResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Tagui AdyanResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Marina StarinovaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Maria KrasnovaResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Andrey VasilyevResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0002-7169-2724
Oleg MakhnachResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0002-2707-8313
Rena ZinchenkoResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.ORCID 0000-0003-3586-3458
Sergey KutsevResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Yasemin GokdemirDivision of Pediatric Pulmonology, Marmara University, 34722 Istanbul, Turkey.
Bülent KaradagDivision of Pediatric Pulmonology, Marmara University, 34722 Istanbul, Turkey.ORCID 0000-0003-0605-8871
Dmitry GoldshteinResearch Centre for Medical Genetics, 1 Moskvorechye St., 115552 Moscow, Russia.
Research Centre for Medical Genetics · RUMarmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogenic variant E92K (c.274G > A) of the

Indexed as

Cystic FibrosisAminopyridinesBenzodioxolesCystic Fibrosis Transmembrane Conductance RegulatorHumansMutationRussiaTurkeyAminopyridinesBenzodioxolesCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorlumacaftorCF RegistryCFTRcystic fibrosis (CF)E92Kforskolin-induced swelling (FIS) assaygenotype–phenotype correlationintestinal current measurements (ICM)intestinal organoidsVX-770 potentiatorVX-809 corrector

Identifiers

PMID37047318
PMCPMC10093870
OpenAlexW4361290004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.