Evidence map›Paper›PMID 37047203›Full record

ReviewInternational journal of molecular sciences2023

3D Tumor Models in Urology.

Jochen Neuhaus, Anja Rabien, Annabell Reinhold, Lisa Koehler, Mandy Berndt-Paetz

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jochen NeuhausDepartment of Urology, Research Laboratory, University Leipzig, D-04103 Leipzig, Germany.ORCID 0000-0003-2484-6994
Anja RabienDepartment of Urology, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, D-10117 Berlin, Germany.ORCID 0000-0003-0124-4878
Annabell ReinholdDepartment of Urology, Research Laboratory, University Leipzig, D-04103 Leipzig, Germany.
Lisa KoehlerDepartment of Urology, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, D-10117 Berlin, Germany.
Mandy Berndt-PaetzDepartment of Urology, Research Laboratory, University Leipzig, D-04103 Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional tumor models have become established in both basic and clinical research. As multicellular systems consisting of tumor and tumor-associated cells, they can better represent tumor characteristics than monocellular 2D cultures. In this review, we highlight the potential applications of tumor spheroids and organoids in the field of urology. Further, we illustrate the generation and characteristics of standardized organoids as well as membrane-based 3D in vitro models in bladder cancer research. We discuss the technical aspects and review the initial successes of molecular analyses in the three major urologic tumor entities: urinary bladder carcinoma (BCa), prostate carcinoma (PCa), and renal cell carcinoma (RCC).

Indexed as

Carcinoma, Renal CellKidney NeoplasmsUrinary Bladder NeoplasmsUrologyCell Culture TechniquesHumansMaleOrganoidsSpheroids, CellularTumor Microenvironment3D cell culture techniquebladder cancerprostate cancerrenal cell carcinoma

Identifiers

PMID37047203
PMCPMC10094462

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.