Evidence map›Paper›PMID 37047196›Full record

ReviewInternational journal of molecular sciences2023

ABC Transporters in Bacterial Nanomachineries.

Florestan L Bilsing, Manuel T Anlauf, Eymen Hachani, Sakshi Khosa, Lutz Schmitt

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Novel anti-virulence strategy againstFrontiers in microbiology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Immunopeptidome Landscape DuringInternational journal of molecular sciences · 2025
    Article
  7. Adaptive Resistance ofMicroorganisms · 2025
    Article
  8. Article
  9. Review
  10. Proteome Changes Induced by Iprodione Exposure in the Pesticide-TolerantInternational journal of molecular sciences · 2024
    Article
  11. Article
  12. Article
  13. Association of ABCG5 and ABCG8 Transporters with Sitosterolemia.Advances in experimental medicine and biology · 2024
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Florestan L BilsingInstitute of Biochemistry, Heinrich Heine University, Universitätsstr. 1, 40225 Düsseldorf, Germany.
Manuel T AnlaufInstitute of Biochemistry, Heinrich Heine University, Universitätsstr. 1, 40225 Düsseldorf, Germany.
Eymen HachaniInstitute of Biochemistry, Heinrich Heine University, Universitätsstr. 1, 40225 Düsseldorf, Germany.ORCID 0000-0001-5810-170X
Sakshi KhosaInstitute of Biochemistry, Heinrich Heine University, Universitätsstr. 1, 40225 Düsseldorf, Germany.
Lutz SchmittInstitute of Biochemistry, Heinrich Heine University, Universitätsstr. 1, 40225 Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DE

Funding

Deutsche Forschungsgemeinschaft Schm1279/17-1Deutsche Forschungsgemeinschaft SFB 1208 project A01
6 · The paper itself

Abstract

Members of the superfamily of ABC transporters are found in all domains of life. Most of these primary active transporters act as isolated entities and export or import their substrates in an ATP-dependent manner across biological membranes. However, some ABC transporters are also part of larger protein complexes, so-called nanomachineries that catalyze the vectorial transport of their substrates. Here, we will focus on four bacterial examples of such nanomachineries: the Mac system providing drug resistance, the Lpt system catalyzing vectorial LPS transport, the Mla system responsible for phospholipid transport, and the Lol system, which is required for lipoprotein transport to the outer membrane of Gram-negative bacteria. For all four systems, we tried to summarize the existing data and provide a structure-function analysis highlighting the mechanistical aspect of the coupling of ATP hydrolysis to substrate translocation.

Indexed as

Adenosine TriphosphateATP-Binding Cassette TransportersBacterial ProteinsBiological TransportCell MembraneProtein TransportAdenosine TriphosphateATP-Binding Cassette TransportersBacterial ProteinsABC transporterLol systemLpt systemMac systemMla systemnanomachineries

Identifiers

PMID37047196
PMCPMC10094684
OpenAlexW4361007877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.