Evidence map›Paper›PMID 37047184›Full record

ArticleInternational journal of molecular sciences2023

Novel Insights in the Potential of Halogenated Polyketide-Peptide Molecules as Lead Compounds in Cancer Drug Discovery.

Valentina Pellicioni, Germana Esposito, Giulia Greco, Ivan Cruz-Chamorro, Fabio Ferrini, Piero Sestili, Roberta Teta, Carmela Fimognari, Valeria Costantino

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Valentina PellicioniDipartimento di Scienze per la Qualità della Vita, Alma Mater Studiorum-Università di Bologna, 47921 Rimini, Italy.
Germana Esposito"TheBlueChemistryLab", Dipartimento di Farmacia, Università di Napoli Federico II, 80131 Napoli, Italy.ORCID 0000-0001-9619-7511
Giulia GrecoDipartimento di Chimica "Giacomo Ciamician", Alma Mater Studiorum-Università di Bologna, 40126 Bologna, Italy.ORCID 0000-0001-8174-9977
Ivan Cruz-ChamorroDepartamento de Bioquímica Médica y Biología Molecular e Inmunología, Facultad de Medicina, Universidad de Sevilla, 41009 Seville, Spain.ORCID 0000-0002-6547-8078
Fabio FerriniDipartimento di Scienze Biomolecolari, Università di Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-3810-1259
Piero SestiliDipartimento di Scienze Biomolecolari, Università di Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0001-9412-1660
Roberta Teta"TheBlueChemistryLab", Dipartimento di Farmacia, Università di Napoli Federico II, 80131 Napoli, Italy.ORCID 0000-0003-0817-7743
Carmela FimognariDipartimento di Scienze per la Qualità della Vita, Alma Mater Studiorum-Università di Bologna, 47921 Rimini, Italy.ORCID 0000-0002-2461-8214
Valeria Costantino"TheBlueChemistryLab", Dipartimento di Farmacia, Università di Napoli Federico II, 80131 Napoli, Italy.ORCID 0000-0001-8723-9505

Funding

Andalusian Government Ministry of Economy, Knowledge, Business, and University DOC_00587/2020University of Seville VII Program of Inner Initiative for Research and Transfer VIIP-PIT-2022-III.2
6 · The paper itself

Abstract

In this interdisciplinary study, we selected two compounds, namely, smenamide A, a peptide-polyketide, and smenolactone D, a polyketide, as models because they are representative of two different classes of molecules isolated from the marine sponge

Indexed as

Antineoplastic AgentsNeoplasmsPolyketidesPoriferaAnimalsChromatography, LiquidDrug DiscoveryPeptidesTandem Mass SpectrometryAntineoplastic AgentsPeptidesPolyketidesapoptosisferroptosisLC-MSlipid peroxidationmolecular networkingnatural productsPCD pathwayspolyketidesmenolactone DSmenospongia aurea

Identifiers

PMID37047184
PMCPMC10094022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.