Evidence map›Paper›PMID 37047126›Full record

ArticleInternational journal of molecular sciences2023

Epstein-Barr Virus Reactivation as a New Predictor of Achieving Remission or Lupus Low Disease Activity State in Patients with Systemic Lupus Erythematosus with Cutaneous Involvement.

Rada Miskovic, Andja Cirkovic, Danijela Miljanovic, Ivica Jeremic, Milka Grk, Milica Basaric, Ivana Lazarevic, Maja Stojanovic, Aleksandra Plavsic, Sanvila Raskovic and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Biomarkers for systemic lupus erythematosus: A scoping review.Immunity, inflammation and disease · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Rada MiskovicClinic of Allergy and Immunology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-0982-2572
Andja CirkovicInstitute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Danijela MiljanovicInstitute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-9446-8701
Ivica JeremicInternal medicine department, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Milka GrkInstitute of Human Genetics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-7534-9608
Milica BasaricInstitute of Rheumatology, 11000 Belgrade, Serbia.
Ivana LazarevicInstitute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-6795-1378
Maja StojanovicClinic of Allergy and Immunology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-4589-7344
Aleksandra PlavsicClinic of Allergy and Immunology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Sanvila RaskovicClinic of Allergy and Immunology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Ana BankoInstitute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-6829-096X
University of Belgrade · RS

Funding

Science Fund of the Republic of Serbia, PROMIS 6060866, ROLERS
6 · The paper itself

Abstract

Although Epstein-Barr virus (EBV) reactivation has long been associated with the pathogenesis of systemic lupus erythematosus (SLE), many aspects of this relationship remain unclear. Our objective was to investigate the association between EBV reactivation and the achievement of SLE remission and lupus low disease activity state (LLDAS) over a six-month period. Clinical, laboratory, and virological tests (anti-EBV antibodies and EBV DNA) were performed among 51 patients with the active form of SLE on two occasions six months apart. SLE remission and LLDAS achievement were assessed at the end of the follow-up period. Active EBV infection was detected in 45% of active SLE patients at baseline, and 77% transitioned to latent EBV infection at six months (

Indexed as

Epstein-Barr Virus InfectionsExanthemaLupus Erythematosus, SystemicCase-Control StudiesHerpesvirus 4, HumanHumansImmunoglobulin MImmunoglobulin Manti-EA (D) IgMbiomarkerEBV reactivationEpstein–Barr virus (EBV)lupus low disease activity statepredictorSLE remissionsystemic lupus erythematosus (SLE)

Identifiers

PMID37047126
PMCPMC10093904
OpenAlexW4360856036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.