ArticleInternational journal of molecular sciences2023
Zinc and Strontium-Substituted Bioactive Glass Nanoparticle/Alginate Composites Scaffold for Bone Regeneration.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
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Who cites it
11 citing papers in PubMed.
- Cytotoxicity evaluation, porosity and physicochemical study of bioactive glass nanocomposites for tissue engineering.Toxicology reports · 2026Article
- Enhanced osteoconductivity of green synthesized hydroxyapatite-functionalized Nd2O3/Fe3O4 nanocomposite using Elaeagnus angustifolia L. seed extract.Stem cell research & therapy · 2025Article
- Novel Antioxidant and Antibacterial Injectable Hydrogels Incorporating Clove Oil-Loaded Mesoporous Bioactive Glass Nanoparticles: A Promising Strategy for Enhanced Bone Regeneration.Macromolecular bioscience · 2025Article
- Nature-Based Hydrogels Combined with Nanoparticles for Bone Regeneration.Journal of functional biomaterials · 2025Review
- Emerging Strategies for Bioactive Agent-Loaded Xenogeneic Bone Scaffolds in Regenerative Medicine: A Comprehensive Review.Drug design, development and therapy · 2025Review
- Biomimetic Natural Biomaterial Nanocomposite Scaffolds: A Rising Prospect for Bone Replacement.International journal of molecular sciences · 2024Review
- Bioactive ceramic-based materials: beneficial properties and potential applications in dental repair and regeneration.Regenerative medicine · 2024Review
- Strontium-Doped Bioglass-Laden Gelatin Methacryloyl Hydrogels for Vital Pulp Therapy.Journal of functional biomaterials · 2024Article
- Characterization of Acellular Cartilage Matrix-Sodium Alginate Scaffolds in Various Proportions.Tissue engineering. Part C, Methods · 2024Article
- Multifunctional bioactive glass nanoparticles: surface-interface decoration and biomedical applications.Regenerative biomaterials · 2024Review
- Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid.Polymers · 2023Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The global population is growing older and entering an aging society. Aging results in severe tissue disorder and organ dysfunction. Bone-related injuries are particularly significant. The need for alternative bone replacement materials for human implants has grown over the past few decades. Alginate has the potential for use as a cell scaffold for bone tissue engineering due to its high bio-compatibility. To improve the bioactivity of alginate scaffolds, zinc- and strontium-containing sol-gel-derived bioactive glass nanoparticles (Zn-Sr-BGNPs) with sizes ranging from 100 to l40 nm were incorporated. Zn-Sr-BGNPs synthesized through the sol-gel process have a high sur-face-to-volume ratio, homogeneity, and purity, resulting in faster degradation. The therapeutic bivalent ions released from Zn-Sr-BGNPs strengthen the cell scaffold and improve the stimulation of the production and development of bone cells. Zn-Sr-BGNPs with different Zn to Si nominal ratios of 0, 1, and 1.5 were mixed with alginate in this research. The ratio of Zn in Zn-Sr-BGNPs and the ratio of Zn-Sr-BGNPs in scaffolds impact the pore size, swelling, and biological properties of synthesized composite scaffolds. The surface area and pore volume of a 1:1 1Zn-Sr-BGNP:Alg composite scaffold were 22.58 m
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Registered trials
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