Evidence map›Paper›PMID 37047093›Full record

ArticleInternational journal of molecular sciences2023

Pablo Agüero-Rabes, Julián Pérez-Pérez, Lucía Cremades-Jimeno, María-Salud García-Ayllón, Adriana Gea-González, María José Sainz, Ignacio Mahillo-Fernández, Raquel Téllez, Blanca Cárdaba, Javier Sáez-Valero and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Pablo Agüero-RabesDepartment of Neurology, Fundación Jiménez Díaz, 28040 Madrid, Spain.
Julián Pérez-PérezSecugen S.L., 28040 Madrid, Spain.ORCID 0000-0001-6091-0012
Lucía Cremades-JimenoDepartment of Immunology, IIS-Fundación Jiménez Díaz-UAM, 28040 Madrid, Spain.ORCID 0000-0002-8094-5295
María-Salud García-AyllónInstituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, 03550 Alicante, Spain.ORCID 0000-0001-5140-9752
Adriana Gea-GonzálezInstituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, 03550 Alicante, Spain.ORCID 0000-0002-6227-6040
María José SainzDepartment of Neurology, Fundación Jiménez Díaz, 28040 Madrid, Spain.
Ignacio Mahillo-FernándezDepartment of Epidemiology and Biostatistics, Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0003-0558-6541
Raquel TéllezDepartment of Immunology, IIS-Fundación Jiménez Díaz-UAM, 28040 Madrid, Spain.
Blanca CárdabaDepartment of Immunology, IIS-Fundación Jiménez Díaz-UAM, 28040 Madrid, Spain.ORCID 0000-0003-0142-9901
Javier Sáez-ValeroInstituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, 03550 Alicante, Spain.ORCID 0000-0001-7480-320X
Estrella Gómez-TortosaDepartment of Neurology, Fundación Jiménez Díaz, 28040 Madrid, Spain.ORCID 0000-0002-5665-3487
Hospital Universitario Fundación Jiménez Díaz · ESBiomedical Research Networking Center on Neurodegenerative Diseases · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESInstituto de Neurociencias · ES

Funding

Ayuda a Neurociencias de Fundación Tatiabna Pérez de Guzmán el Bueno 4564/006Direcció General d'Universitat, Investigació i Ciència, GVA AICO/2018/090Generalitat Valenciana CIACIF/2021/426Instituto de Salud Carlos III (ISCIII) co-funded by the European Union PI20/00469
6 · The paper itself

Abstract

ADAM10 is the main α-secretase acting in the non-amyloidogenic processing of APP. We hypothesized that certain rare

Indexed as

Alzheimer DiseaseADAM10 ProteinADAM ProteinsAged, 80 and overAmyloid beta-Protein PrecursorAmyloid Precursor Protein SecretasesCerebrospinal Fluid ProteinsHumansMembrane ProteinsADAM10 ProteinADAM10 protein, humanADAM ProteinsAmyloid beta-Protein PrecursorAmyloid Precursor Protein SecretasesCerebrospinal Fluid ProteinsMembrane ProteinsADAM10Alzheimer’s diseaseCSF biomarkersdisintegrin metalloproteinase 10 proteingeneticsα-secretase

Identifiers

PMID37047093
PMCPMC10093927
OpenAlexW4360859316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.