ArticleInternational journal of molecular sciences2023
Diagnostic Accuracy of Leucine-Rich α-2-Glycoprotein 1 as a Non-Invasive Salivary Biomarker in Pediatric Appendicitis.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Hyponatremia as a predictor of complicated appendicitis: a systematic review and meta-analysis.Biomarkers in medicine · 2024Pooled it
- Article
- Urine leukocyte count demonstrates limited diagnostic accuracy for complicated appendicitis in children: a retrospective cohort study.European journal of pediatrics · 2026Article
- Analysis of diagnostic efficacy of serum miR-126-5p levels for stratifying severity in pediatric acute appendicitis.BMC pediatrics · 2026Article
- Revealing the multiple faces of LRG1: gene expression, structure, function, and therapeutic potential.Journal of advanced research · 2026Review
- Serum LRG1 as a diagnostic marker of necrotizing enterocolitis in preterm infants.Frontiers in pediatrics · 2026Article
- Diagnostic value of leucine-rich alpha-2-glycoprotein 1 and calprotectin in acute appendicitis: a short review.Biochemia medica · 2025Review
- Salivary Biomarkers in Pediatric Acute Appendicitis: Current Evidence and Future Directions.Children (Basel, Switzerland) · 2025Review
- Salivary C-Reactive Protein: A Non-Invasive Alternative to Serum CRP in Pediatric Acute Appendicitis.Molecules (Basel, Switzerland) · 2025Article
- Utility of serum and urine leucine-rich alpha-2 glycoprotein 1 (LRG1) as predictors of appendicitis and complicated appendicitis in children.Pediatric surgery international · 2025Article
- Acute Appendicitis or Appendiceal Diverticulitis? A Case Report and Systematic Literature Review.Clinics and practice · 2025Review
- PAN-Immune inflammation value: a new biomarker for diagnosing appendicitis in children??BMC pediatrics · 2025Article
- Salivary IL-6 as a Biomarker for Early Childhood and Rampant Caries: Insights from a Cross-Sectional Study.Biomedicines · 2025Article
- Diagnostic Performance of Serum Leucine-Rich Alpha-2-Glycoprotein 1 in Pediatric Acute Appendicitis: A Prospective Validation Study.Biomedicines · 2024Article
- The Impact of Protein Glycosylation on the Identification of Patients with Pediatric Appendicitis.International journal of molecular sciences · 2024Article
- Serum Leucine-Rich α2 Glycoprotein Could Be a Useful Biomarker to Differentiate Patients with Normal Colonic Mucosa from Those with Inflammatory Bowel Disease or Other Forms of Colitis.Journal of clinical medicine · 2024Article
- Oral Infection, Oral Pathology and Salivary Diagnostics of Mpox Disease: Relevance in Dentistry and OMICs Perspectives.International journal of molecular sciences · 2023Review
- Eosinophil Granule Proteins Involvement in Acute Appendicitis-An Allergic Disease?International journal of molecular sciences · 2023Article
- Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study.Children (Basel, Switzerland) · 2023Article
- Measuring Children's Stress via Saliva in Surgical and Endoscopic Procedures and Its Measurement Intention in the Community: Reality-Future Prospects.Children (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study is to evaluate the diagnostic accuracy of leucine-rich α-2-glycoprotein 1 (LRG1) in saliva as a novel biomarker for acute appendicitis in the pediatric population. From October 2021 to June 2022, 92 children aged 5 to 17 years who presented with acute abdomen and suspected acute appendicitis were enrolled in this prospective study. The parameters documented included demographic and clinical information, as well as operative and postoperative data. Patients were divided into two groups: those with acute appendicitis who underwent laparoscopic appendectomy (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.