Evidence map›Paper›PMID 37047012›Full record

ArticleInternational journal of molecular sciences2023

Butein Inhibits Cell Growth by Blocking the IL-6/IL-6Rα Interaction in Human Ovarian Cancer and by Regulation of the IL-6/STAT3/FoxO3a Pathway.

Sun-Ae Park, Young Ju Seo, Lee Kyung Kim, Hee Jung Kim, Kee Dong Yoon, Tae-Hwe Heo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals.Bioengineering (Basel, Switzerland) · 2024
    Review
  4. Review
  5. IL-6 Inhibitory Compounds from the Aerial Parts ofMolecules (Basel, Switzerland) · 2024
    Article
  6. Roles of Phytochemicals in Cancer Prevention and Therapeutics.International journal of molecular sciences · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sun-Ae ParkLaboratory of Pharmacoimmunology, Integrated Research Institute of Pharmaceutical Sciences and BK21 FOUR Team for Advanced Program for Smart Pharma Leaders, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Bucheon 14662, Republic of Korea.ORCID 0000-0001-7940-1242
Young Ju SeoCollege of Pharmacy, The Catholic University of Korea, Bucheon 14662, Republic of Korea.
Lee Kyung KimLaboratory of Pharmacoimmunology, Integrated Research Institute of Pharmaceutical Sciences and BK21 FOUR Team for Advanced Program for Smart Pharma Leaders, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Bucheon 14662, Republic of Korea.ORCID 0000-0002-0225-3170
Hee Jung KimLaboratory of Pharmacoimmunology, Integrated Research Institute of Pharmaceutical Sciences and BK21 FOUR Team for Advanced Program for Smart Pharma Leaders, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Bucheon 14662, Republic of Korea.ORCID 0000-0002-6122-6906
Kee Dong YoonCollege of Pharmacy, The Catholic University of Korea, Bucheon 14662, Republic of Korea.
Tae-Hwe HeoLaboratory of Pharmacoimmunology, Integrated Research Institute of Pharmaceutical Sciences and BK21 FOUR Team for Advanced Program for Smart Pharma Leaders, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Bucheon 14662, Republic of Korea.
Catholic University of Korea · KR

Funding

National Research Foundation of Korea 2018R1A6A1A03025108National Research Foundation of Korea 2021R1A2C2009782National Research Foundation of Korea 2021R1A6A3A1303840811National Research Foundation of Korea 2022R1A2C2009911
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChalconesOvarian NeoplasmsApoptosisCell LineCell Line, TumorCell ProliferationFemaleForkhead Box Protein O3HumansInterleukin-6Receptors, Interleukin-6STAT3 Transcription FactorbuteinChalconesForkhead Box Protein O3FOXO3 protein, humanIL6 protein, humanIL6R protein, humanInterleukin-6Receptors, Interleukin-6STAT3 protein, humanSTAT3 Transcription Factorforkhead box O3a (FoxO3a)interleukin-6 (IL-6)ovarian cancer (OC)signaling pathwaysignal transducer and activator of transcription 3 (STAT3)

Identifiers

PMID37047012
PMCPMC10094418
OpenAlexW4360616242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.