Evidence map›Paper›PMID 37046987›Full record

ReviewInternational journal of molecular sciences2023

The Role of Gasotransmitter-Dependent Signaling Mechanisms in Apoptotic Cell Death in Cardiovascular, Rheumatic, Kidney, and Neurodegenerative Diseases and Mental Disorders.

Stanislav Rodkin, Chizaram Nwosu, Alexander Sannikov, Anton Tyurin, Vasilii Sergeevich Chulkov, Margarita Raevskaya, Alexey Ermakov, Evgeniya Kirichenko, Mitkhat Gasanov

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Role of Hydrogen Sulfide (HInternational journal of molecular sciences · 2023
    Pooled it
  4. Review
  5. Gas entrapping materials for damage control.Advanced drug delivery reviews · 2026
    Review
  6. Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Hydrogen Sulfide Metabolism in the Skin: From Physiology to Malignancy.International journal of molecular sciences · 2025
    Review
  8. Novel neurotherapeutic targets for substance use disorders: Neuroplasticity, neuroinflammation, gasotransmitters and non-canonical organ systems.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Stanislav RodkinFaculty of Bioengineering and Veterinary Medicine, Department of Bioengineering, Don State Technical University, Rostov-on-Don 344000, Russia.ORCID 0000-0003-4036-5410
Chizaram NwosuFaculty of Bioengineering and Veterinary Medicine, Department of Bioengineering, Don State Technical University, Rostov-on-Don 344000, Russia.
Alexander SannikovDepartment of Psychiatry, Rostov State Medical University, Rostov-on-Don 344022, Russia.ORCID 0000-0002-9007-5246
Anton TyurinInternal Medicine Department, Bashkir State Medical University, Ufa 450008, Russia.ORCID 0000-0002-0841-3024
Vasilii Sergeevich ChulkovDepartment of Faculty Therapy, South-Ural State Medical University, Chelyabinsk 454092, Russia.ORCID 0000-0002-0952-6856
Margarita RaevskayaFaculty of Bioengineering and Veterinary Medicine, Department of Bioengineering, Don State Technical University, Rostov-on-Don 344000, Russia.
Alexey ErmakovFaculty of Bioengineering and Veterinary Medicine, Department of Bioengineering, Don State Technical University, Rostov-on-Don 344000, Russia.ORCID 0000-0002-9834-3989
Evgeniya KirichenkoFaculty of Bioengineering and Veterinary Medicine, Department of Bioengineering, Don State Technical University, Rostov-on-Don 344000, Russia.
Mitkhat GasanovDepartment of Internal Diseases #1, Rostov State Medical University, Rostov-on-Don 344022, Russia.ORCID 0000-0001-5856-0404
Don State Technical University · RURostov State Medical University · RUBashkir State Medical University · RUChelyabinsk State Medical Academy · RU

Funding

CSRD VA 1
6 · The paper itself

Abstract

Cardiovascular, rheumatic, kidney, and neurodegenerative diseases and mental disorders are a common cause of deterioration in the quality of life up to severe disability and death worldwide. Many pathological conditions, including this group of diseases, are based on increased cell death through apoptosis. It is known that this process is associated with signaling pathways controlled by a group of gaseous signaling molecules called gasotransmitters. They are unique messengers that can control the process of apoptosis at different stages of its implementation. However, their role in the regulation of apoptotic signaling in these pathological conditions is often controversial and not completely clear. This review analyzes the role of nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (H

Indexed as

GasotransmittersHydrogen SulfideMental DisordersNeurodegenerative DiseasesApoptosisCarbon MonoxideHumansKidneyNitric OxideQuality of LifeCarbon MonoxideGasotransmittersHydrogen SulfideNitric Oxideapoptosiscarbon monoxidecardiovascular diseasescytoprotectiongasotransmittershydrogen sulfidekidney diseasesmental disordersneurodegenerative diseasesnitric oxiderheumatic diseasessulfur dioxide

Identifiers

PMID37046987
PMCPMC10094524
OpenAlexW4360616534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.